TY - JOUR U1 - Zeitschriftenartikel, wissenschaftlich - begutachtet (reviewed) A1 - Rohrbach, Janick A1 - Reinhard, Tobias A1 - Sick, Beate A1 - Dürr, Oliver T1 - Bone erosion scoring for rheumatoid arthritis with deep convolutional neural networks JF - Computers & Electrical Engineering N2 - Rheumatoid arthritis is an autoimmune disease that causes chronic inflammation of synovial joints, often resulting in irreversible structural damage. The activity of the disease is evaluated by clinical examinations, laboratory tests, and patient self-assessment. The long-term course of the disease is assessed with radiographs of hands and feet. The evaluation of the X-ray images performed by trained medical staff requires several minutes per patient. We demonstrate that deep convolutional neural networks can be leveraged for a fully automated, fast, and reproducible scoring of X-ray images of patients with rheumatoid arthritis. A comparison of the predictions of different human experts and our deep learning system shows that there is no significant difference in the performance of human experts and our deep learning model. Y1 - 2019 SN - 0045-7906 SS - 0045-7906 SN - 1879-0755 SS - 1879-0755 U6 - https://doi.org/10.1016/j.compeleceng.2019.08.003 DO - https://doi.org/10.1016/j.compeleceng.2019.08.003 VL - Vol. 78 SP - 472 EP - 481 PB - Elsevier ER -