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Bone erosion scoring for rheumatoid arthritis with deep convolutional neural networks

  • Rheumatoid arthritis is an autoimmune disease that causes chronic inflammation of synovial joints, often resulting in irreversible structural damage. The activity of the disease is evaluated by clinical examinations, laboratory tests, and patient self-assessment. The long-term course of the disease is assessed with radiographs of hands and feet. The evaluation of the X-ray images performed by trained medical staff requires several minutes per patient. We demonstrate that deep convolutional neural networks can be leveraged for a fully automated, fast, and reproducible scoring of X-ray images of patients with rheumatoid arthritis. A comparison of the predictions of different human experts and our deep learning system shows that there is no significant difference in the performance of human experts and our deep learning model.

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Metadaten
Author:Janick Rohrbach, Tobias Reinhard, Beate Sick, Oliver Dürr
DOI:https://doi.org/10.1016/j.compeleceng.2019.08.003
ISSN:0045-7906
Parent Title (English):Computers & Electrical Engineering
Volume:Vol. 78
Document Type:Article
Language:English
Year of Publication:2019
Release Date:2020/01/17
First Page:472
Last Page:481
Institutes:Institut für Optische Systeme - IOS
Relevance:Peer reviewed Publikation in Thomson-Reuters-Listung
Open Access?:Nein
Licence (English):License LogoLizenzbedingungen Elsevier