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Healthy and good sleep is a prerequisite for a rested mind and body. Both form the basis for physical and mental health. Healthy sleep is hindered by sleep disorders, the medically diagnosed frequency of which increases sharply from the age of 40. This chapter describes the formal specification of an on-course practical implementation for a non-invasive system based on biomedical signal processing to support the diagnosis and treatment of sleep-related diseases. The system aims to continuously monitor vital data during sleep in a patient’s home environment over long periods by using non-invasive technologies. At the center of the development is the MORPHEUS Box (MoBo), which consists of five main conceptualizations: the MoBo core, the MoBo-HW, the MoBo algorithm, the MoBo API, and the MoBo app. These synergistic elements aim to support the diagnosis and treatment of sleep-related diseases. Although there are related developments in individual aspects concerning the system, no comparative approach is known that gives a similar scope of functionality, deployment flexibility, extensibility, or the possibility to use multiple user groups. With the specification provided in this chapter, the MORPHEUS project sets a good platform, data model, and transmission strategies to bring an innovative proposal to measure sleep quality and detect sleep diseases from non-invasive sensors.
This paper introduces the third update/release of the Global Sanctions Data Base (GSDB-R3). The GSDB-R3 extends the period of coverage from 1950–2019 to 1950–2022, which includes two special periods—COVID-19 and the new sanctions against Russia. This update of the GSDB contains a total of 1325 cases. In response to multiple inquiries and requests, the GSDB-R3 has been amended with a new variable that distinguishes between unilateral and multilateral sanctions. As before, the GSDB comes in two versions, case-specific and dyadic, which are freely available upon request at GSDB@drexel.edu. To highlight one of the new features of the GSDB, we estimate the heterogeneous effects of unilateral and multilateral sanctions on trade. We also obtain estimates of the effects on trade of the 2014 sanctions on Russia.
We quantify the effects of GATT/WTO membership on trade and welfare. Using an extensive database covering manufacturing trade for 186 countries over the period 1980–2016, we find that the average partial equilibrium impact of GATT/WTO membership on trade among member countries is large, positive, and significant. We contribute to the literature by estimating country-specific estimates and find them to vary widely across the countries in our sample with poorer members benefitting more. Using these estimates, we simulate the general equilibrium effects of GATT/WTO on welfare, which are sizable and heterogeneous across members. We show that countries not experiencing positive trade effects from joining GATT/WTO can still gain in terms of welfare, due to lower import prices and higher export demand.
AbstractSanctions encompass a wide set of policy instruments restricting cross‐border economic activities. In this paper, we study how different types of sanctions affect the export behavior of firms to the targeted countries. We combine Danish register data, including information on firm‐destination‐specific exports, with information on sanctions imposed by Denmark from the Global Sanctions Database. Our data allow us to study firms' export behavior in 62 sanctioned countries, amounting to a total of 453 country‐years with sanctions over the period 2000–2015. Methodologically, we apply a two‐stage estimation strategy to properly account for multilateral resistance terms. We find that, on average, sanctions lead to a significant reduction in firms' destination‐specific exports and a significant increase in firms' probability to exit the destination. Next, we study heterogeneity in the effects of sanctions across (i) sanction types and sanction packages, (ii) the objectives of sanctions, and (iii) countries subject to sanctions. Results confirm that the effects of sanctions on firms' export behavior vary considerably across these three dimensions.
Apnea is a sleep disorder characterized by breathing interruptions during sleep, impacting cardiorespiratory function and overall health. Traditional diagnostic methods, like polysomnography (PSG), are unobtrusive, leading to noninvasive monitoring. This study aims to develop and validate a novel sleep monitoring system using noninvasive sensor technology to estimate cardiorespiratory parameters and detect sleep apnea. We designed a seamless monitoring system integrating noncontact force-sensitive resistor sensors to collect ballistocardiogram signals associated with cardiorespiratory activity. We enhanced the sensor’s sensitivity and reduced the noise by designing a new concept of edge-measuring sensor using a hemisphere dome and mechanical hanger to distribute the force and mechanically amplify the micromovement caused by cardiac and respiration activities. In total, we deployed three edge-measuring sensors, two deployed under the thoracic and one under the abdominal regions. The system is supported with onboard signal preprocessing in multiple physical layers deployed under the mattress. We collected the data in four sleeping positions from 16 subjects and analyzed them using ensemble empirical mode decomposition (EMD) to avoid frequency mixing. We also developed an adaptive thresholding method to identify sleep apnea. The error was reduced to 3.98 and 1.43 beats/min (BPM) in heart rate (HR) and respiration estimation, respectively. The apnea was detected with an accuracy of 87%. We optimized the system such that only one edge-measuring sensor can measure the cardiorespiratory parameters. Such a reduction in the complexity and simplification of the instruction of use shows excellent potential for in-home and continuous monitoring.
Sleep is essential to physical and mental health. However, the traditional approach to sleep analysis—polysomnography (PSG)—is intrusive and expensive. Therefore, there is great interest in the development of non-contact, non-invasive, and non-intrusive sleep monitoring systems and technologies that can reliably and accurately measure cardiorespiratory parameters with minimal impact on the patient. This has led to the development of other relevant approaches, which are characterised, for example, by the fact that they allow greater freedom of movement and do not require direct contact with the body, i.e., they are non-contact. This systematic review discusses the relevant methods and technologies for non-contact monitoring of cardiorespiratory activity during sleep. Taking into account the current state of the art in non-intrusive technologies, we can identify the methods of non-intrusive monitoring of cardiac and respiratory activity, the technologies and types of sensors used, and the possible physiological parameters available for analysis. To do this, we conducted a literature review and summarised current research on the use of non-contact technologies for non-intrusive monitoring of cardiac and respiratory activity. The inclusion and exclusion criteria for the selection of publications were established prior to the start of the search. Publications were assessed using one main question and several specific questions. We obtained 3774 unique articles from four literature databases (Web of Science, IEEE Xplore, PubMed, and Scopus) and checked them for relevance, resulting in 54 articles that were analysed in a structured way using terminology. The result was 15 different types of sensors and devices (e.g., radar, temperature sensors, motion sensors, cameras) that can be installed in hospital wards and departments or in the environment. The ability to detect heart rate, respiratory rate, and sleep disorders such as apnoea was among the characteristics examined to investigate the overall effectiveness of the systems and technologies considered for cardiorespiratory monitoring. In addition, the advantages and disadvantages of the considered systems and technologies were identified by answering the identified research questions. The results obtained allow us to determine the current trends and the vector of development of medical technologies in sleep medicine for future researchers and research.
Short-Term Density Forecasting of Low-Voltage Load using Bernstein-Polynomial Normalizing Flows
(2023)
The transition to a fully renewable energy grid requires better forecasting of demand at the low-voltage level to increase efficiency and ensure reliable control. However, high fluctuations and increasing electrification cause huge forecast variability, not reflected in traditional point estimates. Probabilistic load forecasts take uncertainties into account and thus allow more informed decision-making for the planning and operation of low-carbon energy systems. We propose an approach for flexible conditional density forecasting of short-term load based on Bernstein polynomial normalizing flows, where a neural network controls the parameters of the flow. In an empirical study with 3639 smart meter customers, our density predictions for 24h-ahead load forecasting compare favorably against Gaussian and Gaussian mixture densities. Furthermore, they outperform a non-parametric approach based on the pinball loss, especially in low-data scenarios.
Multi-faceted stresses of social, environmental, and economic nature are increasingly challenging the existence and sustainability of our societies. Cities in particular are disproportionately threatened by global issues such as climate change, urbanization, population growth, air pollution, etc. In addition, urban space is often too limited to effectively develop sustainable, nature-based solutions while accommodating growing populations. This research aims to provide new methodologies by proposing lightweight green bridges in inner-city areas as an effective land value capture mechanism. Geometry analysis was performed using geospatial and remote sensing data to provide geometrically feasible locations of green bridges. A multi-criteria decision analysis was applied to identify suitable locations for green bridges investigating Central European urban centers with a focus on German cities as representative examples. A cost-benefit analysis was performed to assess the economic feasibility using a case study. The results of the geometry analysis identified 3249 locations that were geometrically feasible to implement a green bridge in German cities. The sample locations from the geometry analysis were proved to be validated for their implementation potential. Multi-criteria decision analysis was used to select 287 sites that fall under the highest suitable class based on several criteria. The cost-benefit analysis of the case study showed that the market value of the property alone can easily outweigh the capital and maintenance costs of a green bridge, while the indirect (monetary) benefits of the green space continue to increase the overall value of the green bridge property including its neighborhood over time. Hence, we strongly recommend light green bridges as financially sustainable and nature-based solutions in cities worldwide.
Sanktionen stellen Zwangsmaßnahmen dar, die bei der Bewältigung politischer Spannungen zwischen Nationen eine lange und wiederkehrende Stellung einnehmen. Sie werden sowohl einseitig als auch in Staatenbündnissen verhängt und besonders nach dem 2. Weltkrieg mit zunehmender Häufigkeit eingesetzt. Während im letzten Jahrhundert, insbesondere vor dem 2. Weltkrieg, Handelsbeschränkungen und umfassende Wirtschaftsblockaden die vorherrschenden Sanktionsinstrumente darstellten, werden heute in einer stärker integrierten und globalisierten Welt Sanktionen in verschiedenen weiteren Formen verhängt, einschließlich internationaler Finanzbeschränkungen, Reiseverbote, Handelseinschränkungen für bestimmte Gütergruppen, Aufhebung militärischer Hilfen und spezifische Einschränkungen, wie beispielsweise Flugverbote und Hafensperrungen.
Insecurity Refactoring is a change to the internal structure of software to inject a vulnerability without changing the observable behavior in a normal use case scenario. An implementation of Insecurity Refactoring is formally explained to inject vulnerabilities in source code projects by using static code analysis. It creates learning examples with source code patterns from known vulnerabilities.
Insecurity Refactoring is achieved by creating an Adversary Controlled Input Dataflow tree based on a Code Property Graph. The tree is used to find possible injection paths. Transformation of the possible injection paths allows to inject vulnerabilities. Insertion of data flow patterns introduces different code patterns from related Common Vulnerabilities and Exposures (CVE) reports. The approach is evaluated on 307 open source projects. Additionally, insecurity-refactored projects are deployed in virtual machines to be used as learning examples. Different static code analysis tools, dynamic tools and manual inspections are used with modified projects to confirm the presence of vulnerabilities.
The results show that in 8.1% of the open source projects it is possible to inject vulnerabilities. Different inspected code patterns from CVE reports can be inserted using corresponding data flow patterns. Furthermore the results reveal that the injected vulnerabilities are useful for a small sample size of attendees (n=16). Insecurity Refactoring is useful to automatically generate learning examples to improve software security training. It uses real projects as base whereas the injected vulnerabilities stem from real CVE reports. This makes the injected vulnerabilities unique and realistic.