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Respiratory diseases are leading causes of death and disability in the world. The recent COVID-19 pandemic is also affecting the respiratory system. Detecting and diagnosing respiratory diseases requires both medical professionals and the clinical environment. Most of the techniques used up to date were also invasive or expensive.
Some research groups are developing hardware devices and techniques to make possible a non-invasive or even remote respiratory sound acquisition. These sounds are then processed and analysed for clinical, scientific, or educational purposes.
We present the literature review of non-invasive sound acquisition devices and techniques.
The results are about a huge number of digital tools, like microphones, wearables, or Internet of Thing devices, that can be used in this scope.
Some interesting applications have been found. Some devices make easier the sound acquisition in a clinic environment, but others make possible daily monitoring outside that ambient. We aim to use some of these devices and include the non-invasive recorded respiratory sounds in a Digital Twin system for personalized health.
This work is a study about a comparison of survey tools and it should help developers in selecting a suited tool for application in an AAL environment. The first step was to identify the basic required functionality of the survey tools used for AAL technologies and to compare these tools by their functionality and assignments. The comparative study was derived from the data obtained, previous literature studies and further technical data. A list of requirements was stated and ordered in terms of relevance to the target application domain. With the help of an integrated assessment method, the calculation of a generalized estimate value was performed and the result is explained. Finally, the planned application of this tool in a running project is explained.
In diesem Beitrag wird eine Methode des maschinellen Lernens entwickelt, die die Schlafstadienerkennung untersucht. Übliche Methoden der Schlafanalyse basieren auf der Polysomnographie (PSG). Der präsentierte Ansatz basiert auf Signalen, die ausschließlich nicht-invasiv in einer häuslichen Umgebung gemessen werden können. Bewegungs-, Herzschlags- und Atmungssignale können vergleichsweise leicht erfasst werden aber die Erkennung der Schlafstadien ist dadurch erschwert. Die Signale werden als Zeitreihenfolge strukturiert und in Epochen überführt. Die Leistungsfähigkeit von maschinellem Lernen wird der Polysomnographie gegenübergestellt und bewertet.
Long-term sleep monitoring can be done primarily in the home environment. Good patient acceptance requires low user and installation barriers. The selection of parameters in this approach is significantly limited compared to a PSG session. The aim is a qualified selection of parameters, which on the one hand allow a sufficiently good classification of sleep phases and on the other hand can be detected by non-invasive methods.
The goal of the presented project is to develop the concept of home ehealth centers for barrier-free and cross-border telemedicine. AAL technologies are already present on the market but there is still a gap to close until they can be used for ordinary patient needs. The general idea needs to be accompanied by new services, which should be brought together in order to provide a full coverage of service for the users. Sleep and stress were chosen as predominant diseases for a detailed study within this project because of their widespread influence in the population. The executed scientific study of available home devices analyzing sleep has provided the necessary to select appropriate devices. The first choice for the project implementation is the device EMFIT QS+. This equipment provides a part of a complete system that a home telemedical hospital can provide at a level of precision and communication with internal and/or external health services.
Für die Überwachung des Schlafs zu Hause sind nichtinvasive Methoden besonders gut anwendbar. Die Signale, die häufig überwacht werden, sind Herzfrequenz und Atemfrequenz. Die Ballistokardiographie (BCG)ist eine Technik, bei der die Herzfrequenz aus den mechanischen Schwingungen des Körpers bei jedem Herzzyklus gemessen wird. Kürzlich wurden Übersichtsarbeiten veröffentlicht. Die Untersuchung soll in einem ersten Ansatz bewerten, ob die Herzfrequenz anhand von BCG erkannt werden kann. Die wesentlichen Randbedingungen sind, ob dies gelingt, wenn der Sensor unter der Matratze positioniert wird und kostengünstige Sensoren zum Einsatz kommen.
Methods based exclusively on heart rate hardly allow to differentiate between physical activity, stress, relaxation, and rest, that is why an additional sensor like activity/movement sensor added for detection and classification. The response of the heart to physical activity, stress, relaxation, and no activity can be very similar. In this study, we can observe the influence of induced stress and analyze which metrics could be considered for its detection. The changes in the Root Mean Square of the Successive Differences provide us with information about physiological changes. A set of measurements collecting the RR intervals was taken. The intervals are used as a parameter to distinguish four different stages. Parameters like skin conductivity or skin temperature were not used because the main aim is to maintain a minimum number of sensors and devices and thereby to increase the wearability in the future.
The investigation of stress requires to distinguish between stress caused by physical activity and stress that is caused by psychosocial factors. The behaviour of the heart in response to stress and physical activity is very similar in case the set of monitored parameters is reduced to one. Currently, the differentiation remains difficult and methods which only use the heart rate are not able to differentiate between stress and physical activity, without using additional sensor data input. The approach focusses on methods which generate signals providing characteristics that are useful for detecting stress, physical activity, no activity and relaxation.
In previous studies, we used a method for detecting stress that was based exclusively on heart rate and ECG for differentiation between such situations as mental stress, physical activity, relaxation, and rest. As a response of the heart to these situations, we observed different behavior in the Root Mean Square of the Successive differences heartbeats (RMSSD). This study aims to analyze Virtual Reality via a virtual reality headset as an effective stressor for future works. The value of the Root Mean Square of the Successive Differences is an important marker for the parasympathetic effector on the heart and can provide information about stress. For these measurements, the RR interval was collected using a breast belt. In these studies, we can observe the Root Mean Square of the successive differences heartbeats. Additional sensors for the analysis were not used. We conducted experiments with ten subjects that had to drive a simulator for 25 minutes using monitors and 25 minutes using virtual reality headset. Before starting and after finishing each simulation, the subjects had to complete a survey in which they had to describe their mental state. The experiment results show that driving using virtual reality headset has some influence on the heart rate and RMSSD, but it does not significantly increase the stress of driving.
Cardiovascular diseases are directly or indirectly responsible for up to 38.5% of all deaths in Germany and thus represent the most frequent cause of death. At present, heart diseases are mainly discovered by chance during routine visits to the doctor or when acute symptoms occur. However, there is no practical method to proactively detect diseases or abnormalities of the heart in the daily environment and to take preventive measures for the person concerned. Long-term ECG devices, as currently used by physicians, are simply too expensive, impractical, and not widely available for everyday use. This work aims to develop an ECG device suitable for everyday use that can be worn directly on the body. For this purpose, an already existing hardware platform will be analyzed, and the corresponding potential for improvement will be identified. A precise picture of the existing data quality is obtained by metrological examination, and corresponding requirements are defined. Based on these identified optimization potentials, a new ECG device is developed. The revised ECG device is characterized by a high integration density and combines all components directly on one board except the battery and the ECG electrodes. The compact design allows the device to be attached directly to the chest. An integrated microcontroller allows digital signal processing without the need for an additional computer. Central features of the evaluation are a peak detection for detecting R-peaks and a calculation of the current heart rate based on the RR interval. To ensure the validity of the detected R-peaks, a model of the anatomical conditions is used. Thus, unrealistic RR-intervals can be excluded. The wireless interface allows continuous transmission of the calculated heart rate. Following the development of hardware and software, the results are verified, and appropriate conclusions about the data quality are drawn. As a result, a very compact and wearable ECG device with different wireless technologies, data storage, and evaluation of RR intervals was developed. Some tests yelled runtimes up to 24 hours with wireless Lan activated and streaming.