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Sleep disorders can impact daily life, affecting physical, emotional, and cognitive well-being. Due to the time-consuming, highly obtrusive, and expensive nature of using the standard approaches such as polysomnography, it is of great interest to develop a noninvasive and unobtrusive in-home sleep monitoring system that can reliably and accurately measure cardiorespiratory parameters while causing minimal discomfort to the user’s sleep. We developed a low-cost Out of Center Sleep Testing (OCST) system with low complexity to measure cardiorespiratory parameters. We tested and validated two force-sensitive resistor strip sensors under the bed mattress covering the thoracic and abdominal regions. Twenty subjects were recruited, including 12 males and 8 females. The ballistocardiogram signal was processed using the 4th smooth level of the discrete wavelet transform and the 2nd order of the Butterworth bandpass filter to measure the heart rate and respiration rate, respectively. We reached a total error (concerning the reference sensors) of 3.24 beats per minute and 2.32 rates for heart rate and respiration rate, respectively. For males and females, heart rate errors were 3.47 and 2.68, and respiration rate errors were 2.32 and 2.33, respectively. We developed and verified the reliability and applicability of the system. It showed a minor dependency on sleeping positions, one of the major cumbersome sleep measurements. We identified the sensor under the thoracic region as the optimal configuration for cardiorespiratory measurement. Although testing the system with healthy subjects and regular patterns of cardiorespiratory parameters showed promising results, further investigation is required with the bandwidth frequency and validation of the system with larger groups of subjects, including patients.
Ballistocardiography (BCG) can be used to monitor heart rate activity. Besides, the accelerometer should have high sensitivity and minimal internal noise; a low-cost approach was taken into consideration. Several measurements have been executed to determine the optimal positioning of a sensor under the mattress to obtain a signal strong enough for further analysis. A prototype for an unobtrusive accelerometer-based measurement system has been developed and tested in a conventional bed without any specific extras. The influence of the human sleep position for the output accelerometer data was tested. The obtained results indicate the potential to capture BCG signals using accelerometers. The measurement system can detect heart rate in an unobtrusive form in the home environment.
Due to the rising need for palliative care in Russia, it is crucial to provide timely and high-quality solutions for patients, relatives, and caregivers. A methodology for remote monitoring of patients in need of palliative care and the requirements will be developed for a hardware-software complex for remote monitoring of patients' health at home.
The digital twin concept has been widely known for asset monitoring in the industry for a long time. A clear example is the automotive industry. Recently, there has also been significant interest in the application of digital twins in healthcare, especially in genomics in what is known as precision medicine. This work focuses on another medical speciality where digital twins can be applied, sleep medicine. However, there is still great controversy about the fundamentals that constitute digital twins, such as what this concept is based on and how it can be included in healthcare effectively and sustainably. This article reviews digital twins and their role so far in what is known as personalized medicine. In addition, a series of steps will be exposed for a possible implementation of a digital twin for a patient suffering from sleep disorders. For this, artificial intelligence techniques, clinical data management, and possible solutions for explaining the results derived from artificial intelligence models will be addressed.
Globalization has increased the number of road trips and vehicles. The result has been an intensification of traffic accidents, which are becoming one of the most important causes of death worldwide. Traffic accidents are often due to human error, the probability of which increases when the cognitive ability of the driver decreases. Cognitive capacity is closely related to the driver’s mental state, as well as other external factors such as the CO2 concentration inside the vehicle. The objective of this work is to analyze how these elements affect driving. We have conducted an experiment with 50 drivers who have driven for 25 min using a driving simulator. These drivers completed a survey at the start and end of the experiment to obtain information about their mental state. In addition, during the test, their stress level was monitored using biometric sensors and the state of the environment (temperature, humidity and CO2 level) was recorded. The results of the experiment show that the initial level of stress and tiredness of the driver can have a strong impact on stress, driving behavior and fatigue produced by the driving test. Other elements such as sadness and the conditions of the interior of the vehicle also cause impaired driving and affect compliance with traffic regulations.
Autism spectrum disorders (ASD) affect a large number of children both in the Russian Federation and in Germany. Early diagnosis is key for these children, because the sooner parents notice such disorders in a child and the rehabilitation and treatment program starts, the higher the likelihood of his social adaptation. The difficulties in raising such a child lie in the complexity of his learning outside of children's groups and the complexity of his medical care. In this regard, the development of digital applications that facilitate medical care and education of such children at home is important and relevant. The purpose of the project is to improve the availability and quality of healthcare and social adaptation at home of children with ASD through the use of digital technologies.
Stress is becoming an important topic in modern life. The influence of stress results in a higher rate of health disorders such as burnout, heart problems, obesity, asthma, diabetes, depressions and many others. Furthermore individual’s behavior and capabilities could be directly affected leading to altered cognition, inappropriate decision making and problem solving skills. In a dynamic and unpredictable environment, such as automotive, this can result in a higher risk for accidents. Different papers faced the estimation as well as prediction of drivers’ stress level during driving. Another important question is not only the stress level of the driver himself, but also the influence on and of a group of other drivers in the near area. This paper proposes a system, which determines a group of drivers in a near area as clusters and it derives the individual stress level. This information will be analyzed to generate a stress map, which represents a graphical view about road section with a higher stress influence. Aggregated data can be used to generate navigation routes with a lower stress influence to decrease stress influenced driving as well as improve road safety.
Stress is recognized as a predominant disease with raising costs for rehabilitation and treatment. Currently there several different approaches that can be used for determining and calculating the stress levels. Usually the methods for determining stress are divided in two categories. The first category do not require any special equipment for measuring the stress. This category useless the variation in the behaviour patterns that occur while stress. The core disadvantage for the category is their limitation to specific use case. The second category uses laboratories instruments and biological sensors. This category allow to measure stress precisely and proficiently but on the same time they are not mobile and transportable and do not support real-time feedback. This work presents a mobile system that provides the calculation of stress. For achieving this, the of a mobile ECG sensor is analysed, processed and visualised over a mobile system like a smartphone. This work also explains the used stress measurement algorithm. The result of this work is a portable system that can be used with a mobile system like a smartphone as visual interface for reporting the current stress level.
Personalized remote healthcare monitoring is in continuous development due to the technology improvements of sensors and wearable electronic systems. A state of the art of research works on wearable sensors for healthcare applications is presented in this work. Furthermore, a state of the art of wearable devices, chest and wrist band and smartwatches available on the market for health and sport monitoring is presented in this paper. Many activity trackers are commercially available. The prices are continuously reducing and the performances are improving, but commercial devices do not provide raw data and are therefore not useful for research purposes.
This paper compares two popular scripting implementations for hardware prototyping: Python scripts exe- cut from User-Space and C-based Linux-Driver processes executed from Kernel-Space, which can provide information to researchers when considering one or another in their implementations. Conclusions exhibit that deploying software scripts in the kernel space makes it possible to grant a certain quality of sensor information using a Raspberry Pi without the need for advanced real-time operational systems.
To evaluate the quality of a person's sleep it is essential to identify the sleep stages and their durations. Currently, the gold standard in terms of sleep analysis is overnight polysomnography (PSG), during which several techniques like EEG (eletroencephalogram), EOG (electrooculogram), EMG (electromyogram), ECG (electrocardiogram), SpO2 (blood oxygen saturation) and for example respiratory airflow and respiratory effort are recorded. These expensive and complex procedures, applied in sleep laboratories, are invasive and unfamiliar for the subjects and it is a reason why it might have an impact on the recorded data. These are the main reasons why low-cost home diagnostic systems are likely to be advantageous. Their aim is to reach a larger population by reducing the number of parameters recorded. Nowadays, many wearable devices promise to measure sleep quality using only the ECG and body-movement signals. This work presents an android application developed in order to proof the accuracy of an algorithm published in the sleep literature. The algorithm uses ECG and body movement recordings to estimate sleep stages. The pre-recorded signals fed into the algorithm have been taken from physionet1 online database. The obtained results have been compared with those of the standard method used in PSG. The mean agreement ratios between the sleep stages REM, Wake, NREM-1, NREM-2 and NREM-3 were 38.1%, 14%, 16%, 75% and 54.3%.
The respiratory rate is a vital sign indicating breathing illness. It is necessary to analyze the mechanical oscillations of the patient's body arising from chest movements. An inappropriate holder on which the sensor is mounted, or an inappropriate sensor position is some of the external factors which should be minimized during signal registration. This paper considers using a non-invasive device placed under the bed mattress and evaluates the respiratory rate. The aim of the work is the development of an accelerometer sensor holder for this system. The normal and deep breathing signals were analyzed, corresponding to the relaxed state and when taking deep breaths. The evaluation criterion for the holder's model is its influence on the patient's respiratory signal amplitude for each state. As a result, we offer a non-invasive system of respiratory rate detection, including the mechanical component providing the most accurate values of mentioned respiratory rate.
This paper presents a bed system able to analyze a person’s movement, breathing and recognize the positions that the subject is lying on the bed during the night without any additional physical contact. The measurements are performed with sensors placed between the mattress and the bed-frame. An Intel Edison board was used as an endpoint that served as a communication node from the mesh network to external service. Two nodes and Intel Edison are attached to the bottom of the bed frame and they are connected to the sensors. First test results have indicated the potential of the proposed approach for the recognition of sleep positions with 83% of correct recognized positions.
The process of restoring our body and brain from fatigue is directly depend-ing on the quality of sleep. It can be determined from the report of the sleep study results. Classification of sleep stages is the first step of this study and this includes the measurement of biovital data and its further processing.
In this work, the sleep analysis system is based on a hardware sensor net, namely a grid of 24 pressure sensors, supporting sleep phase recognition. In comparison to the leading standard, which is polysomnography, the proposed approach is a non-invasive system. It recognises respiration and body move-ment with only one type of low-cost pressure sensors forming a mesh archi-tecture. The nodes implement as a series of pressure sensors connected to a low-power and performant microcontroller. All nodes are connected via a system wide bus with address arbitration. The embedded processor is the mesh network endpoint that enables network configuration, storing and pre-processing of the data, external data access and visualization.
The system was tested by executing experiments recording the sleep of different healthy young subjects. The results obtained have indicated the po-tential to detect breathing rate and body movement. A major difference of this system in comparison to other approaches is the innovative way to place the sensors under the mattress. This characteristic facilitates the continuous using of the system without any influence on the common sleep process.
Methods based exclusively on heart rate hardly allow to differentiate between physical activity, stress, relaxation, and rest, that is why an additional sensor like activity/movement sensor added for detection and classification. The response of the heart to physical activity, stress, relaxation, and no activity can be very similar. In this study, we can observe the influence of induced stress and analyze which metrics could be considered for its detection. The changes in the Root Mean Square of the Successive Differences provide us with information about physiological changes. A set of measurements collecting the RR intervals was taken. The intervals are used as a parameter to distinguish four different stages. Parameters like skin conductivity or skin temperature were not used because the main aim is to maintain a minimum number of sensors and devices and thereby to increase the wearability in the future.
We consider the problem of increasing the informative value of electrocardiographic (ECG) surveys using data from multichannel electrocardiographic leads, that include both recorded electrocardiosignals and the coordinates of the electrodes placed on the surface of the human torso. In this area, we were interested in reconstruction of the surface distribution of the equivalent sources during the cardiac cycle at relatively low hardware cost. In our work, we propose to reconstruct the equivalent electrical sources by numerical methods, based on integral connection between the density of electrical sources and potential in a conductive medium. We consider maps of distributions of equivalent electric sources on the heart surface (HSSM), presenting source distributions in the form of a simple or double electrical layer. We indicate the dynamics of the heart electrical activity by the space-time mapping of equivalent electrical sources in HSSM.
The recovery of our body and brain from fatigue directly depends on the quality of sleep, which can be determined from the results of a sleep study. The classification of sleep stages is the first step of this study and includes the measurement of vital data and their further processing. The non-invasive sleep analysis system is based on a hardware sensor network of 24 pressure sensors providing sleep phase detection. The pressure sensors are connected to an energy-efficient microcontroller via a system-wide bus. A significant difference between this system and other approaches is the innovative way in which the sensors are placed under the mattress. This feature facilitates the continuous use of the system without any noticeable influence on the sleeping person. The system was tested by conducting experiments that recorded the sleep of various healthy young people. Results indicate the potential to capture respiratory rate and body movement.
This document presents an algorithm for a non-obtrusive recognition of Sleep/Wake states using signals derived from ECG, respiration, and body movement captured while lying in a bed. As a core mathematical base of system data analytics, multinomial logistic regression techniques were chosen. Derived parameters of the three signals are used as the input for the proposed method. The overall achieved accuracy rate is 84% for Wake/Sleep stages, with Cohen’s kappa value 0.46. The presented algorithm should support experts in analyzing sleep quality in more detail. The results confirm the potential of this method and disclose several ways for its improvement.
With the advancement in sensor technology and the trend shift of health measurement from treatment after diagnosis to abnormalities detection long before the occurrence, the approach of turning private spaces into diagnostic spaces has gained much attention. In this work, we designed and implemented a low-cost and compact form factor module that can be deployed on the steering wheel of cars as well as most frequently touch objects at home in order to measure physiological signals from the fingertip of the subject as well as environmental parameters. We estimated the heart rate and SpO2 with the error of 2.83 bpm and 3.52%, respectively. The signal evaluation of skin temperature shows a promising output with respect to environmental recalibration. In addition, the electrodermal activity sensor followed the reference signal, appropriately which indicates the potential for further development and application in stress measurement.
Preliminary results of homomorphic deconvolution application to surface EMG signals during walking
(2021)
Homomorphic deconvolution is applied to sEMG signals recorded during walking. Gastrocnemius lateralis and tibialis anterior signals were acquired according to SENIAM recommendation. MUAP parameters like amplitude and scale were estimated, whilst the MUAP shape parameter was fixed. This features a useful time-frequency representation of sEMG signal. Estimation of scale MUAP parameter was verified extracting the mean frequency of filtered EMG signal, extracted from the scale parameter estimated with two different MUAP shape values.
The number of home office workers sitting for many hours is increasing. The sensor chair is tracking users’ sitting behavior which the help of pressure sensors and tries to avoid wrong postures which may cause diseases. The system provides live monitoring of the pressure distribution via web interface, as well as sitting posture prediction in real time. Posture analysis is realized through machine learning algorithm using a decision tree classifier that is compared to a random forest. Data acquisition and aggregation for the learning process happens with a mobile app adding users biometrical data and the taken sitting posture as label. The sensor chair is able to differentiate between an arched back, a neutral posture or a laid back position taken on the chair. The classifier achieves an accuracy of 97.4% on our test set and is comparable to the performance of the random forest with 98.9%.
The overall goal of this work is to detect and analyze a person's movement, breathing and heart rate during sleep in a common bed overnight without any additional physical contact. The measurement is performed with the help of
sensors placed between the mattress and the frame. A two-stage pattern classification algorithm based has been implemented that applies statistics analysis to recognize the position of patients. The system is implemented in a sensors-network, hosting several nodes and communication end-points to support quick and efficient classification. The overall tests show convincing results for the position recognition and a reasonable overlap in matching.
Assistive environments are entering our homes faster than ever. However, there are still various barriers to be broken. One of the crucial points is a personalization of offered services and integration of assistive technologies in common objects and therefore in a regular daily routine. Recognition of sleep patterns for the preliminary sleep study is one of the health services that could be performed in an undisturbing way. This article proposes the hardware system for the measurement of bio-vital signals necessary for initial sleep study in a non-obtrusive way. The first results confirm the potential of measurement of breathing and movement signals with the proposed system.
Sleep is an important aspect in life of every human being. The average sleep duration for an adult is approximately 7 h per day. Sleep is necessary to regenerate physical and psychological state of a human. A bad sleep quality has a major impact on the health status and can lead to different diseases. In this paper an approach will be presented, which uses a long-term monitoring of vital data gathered by a body sensor during the day and the night supported by mobile application connected to an analyzing system, to estimate sleep quality of its user as well as give recommendations to improve it in real-time. Actimetry and historical data will be used to improve the individual recommendations, based on common techniques used in the area of machine learning and big data analysis.
Monitoring heart rate and breathing is essential in understanding the physiological processes for sleep analysis. Polysomnography (PSG) system have traditionally been used for sleep monitoring, but alternative methods can help to make sleep monitoring more portable in someone's home. This study conducted a series of experiments to investigate the use of pressure sensors placed under the bed as an alternative to PSG for monitoring heart rate and breathing during sleep. The following sets of experiments involved the addition of small rubber domes - transparent and black - that were glued to the pressure sensor. The resulting data were compared with the PSG system to determine the accuracy of the pressure sensor readings. The study found that the pressure sensor provided reliable data for extracting heart rate and respiration rate, with mean absolute errors (MAE) of 2.32 and 3.24 for respiration and heart rate, respectively. However, the addition of small rubber hemispheres did not significantly improve the accuracy of the readings, with MAEs of 2.3 bpm and 7.56 breaths per minute for respiration rate and heart rate, respectively. The findings of this study suggest that pressure sensors placed under the bed may serve as a viable alternative to traditional PSG systems for monitoring heart rate and breathing during sleep. These sensors provide a more comfortable and non-invasive method of sleep monitoring. However, the addition of small rubber domes did not significantly enhance the accuracy of the readings, indicating that it may not be a worthwhile addition to the pressure sensor system.
Stress and physical activities are important aspects of life of people. Body reactions on stress and on physical activities can be very similar but long-term stress leads to diseases and damages the body. Currently there is no method to differentiate easily and clearly between these two aspects in a time slot. We have confronted this problem while developing a mobile system for detection and analysis of stress. This paper presents an approach, which uses a long-term monitor with ECG/EKG capabilities and analysis of the heart rate data that is extracted from the device. The focus of the work is to find characteristics that are useful for differentiation between physical activity and stress.
To assess the quality of a person’s sleep, it is essential to examine the sleep behaviour by identifying the several sleep stages, their durations and sleep cycles. The established and gold standard procedure for sleep stage scoring is overnight polysomnography (PSG) with the Rechtschaffen and Kales (R-K) method. Unfortunately, the conduct of PSG is timeconsuming and unfamiliar for the subjects and might have an impact of the recorded data. To avoid the disadvantages with PSG, it is important to make further investigations in low-cost home diagnostic systems. For this intention it is necessary to find suitable bio vital parameters for classifying sleep stages without any physical impairments at the same time.
Due to the promising results in several publications we want to analyse existing methods for sleep stage classification based on the parameters body movement,
heartbeat and respiration. Our aim was to find different behaviour patterns in the several sleep stages. Therefore, the average values of 15 wholenight PSG recordings -obtained from the ‘DREAMS Subjects Database’- where analysed in the light of heartbeat, body movement and respiration with 10 different methods.
Background: Polysomnography (PSG) is the gold standard for detecting obstructive sleep apnea (OSA). However, this technique has many disadvantages when using it outside the hospital or for daily use. Portable monitors (PMs) aim to streamline the OSA detection process through deep learning (DL).
Materials and methods: We studied how to detect OSA events and calculate the apnea-hypopnea index (AHI) by using deep learning models that aim to be implemented on PMs. Several deep learning models are presented after being trained on polysomnography data from the National Sleep Research Resource (NSRR) repository. The best hyperparameters for the DL architecture are presented. In addition, emphasis is focused on model explainability techniques, concretely on Gradient-weighted Class Activation Mapping (Grad-CAM).
Results: The results for the best DL model are presented and analyzed. The interpretability of the DL model is also analyzed by studying the regions of the signals that are most relevant for the model to make the decision. The model that yields the best result is a one-dimensional convolutional neural network (1D-CNN) with 84.3% accuracy.
Conclusion: The use of PMs using machine learning techniques for detecting OSA events still has a long way to go. However, our method for developing explainable DL models demonstrates that PMs appear to be a promising alternative to PSG in the future for the detection of obstructive apnea events and the automatic calculation of AHI.
Polysomnography is a gold standard for a sleep study, and it provides very accurate results, but its cost (both personnel and material) are quite high. Therefore, the development of a low-cost system for overnight breathing and heartbeat monitoring, which provides more comfort while recording the data, is a well-motivated challenge. The system proposed in this manuscript is based on the usage of resistive pressure sensors installed under the mattress. These sensors can measure slight pressure changes provoked during breathing and heartbeat. The captured signal requires advanced processing, like applying filters and amplifiers before the analog signal is ready for the next step. Then, the output signal is digitalized and further processed by an algorithm that performs a custom filtering before it can recognize breathing and heart rate in real-time. The result can be directly visualized. Furthermore, a CSV file is created containing the raw data, timestamps, and unique IDs to facilitate further processing. The achieved results are promising, and the average deviation from a reference device is about 4bpm.
Healthy and good sleep is a prerequisite for a rested mind and body. Both form the basis for physical and mental health. Healthy sleep is hindered by sleep disorders, the medically diagnosed frequency of which increases sharply from the age of 40. This chapter describes the formal specification of an on-course practical implementation for a non-invasive system based on biomedical signal processing to support the diagnosis and treatment of sleep-related diseases. The system aims to continuously monitor vital data during sleep in a patient’s home environment over long periods by using non-invasive technologies. At the center of the development is the MORPHEUS Box (MoBo), which consists of five main conceptualizations: the MoBo core, the MoBo-HW, the MoBo algorithm, the MoBo API, and the MoBo app. These synergistic elements aim to support the diagnosis and treatment of sleep-related diseases. Although there are related developments in individual aspects concerning the system, no comparative approach is known that gives a similar scope of functionality, deployment flexibility, extensibility, or the possibility to use multiple user groups. With the specification provided in this chapter, the MORPHEUS project sets a good platform, data model, and transmission strategies to bring an innovative proposal to measure sleep quality and detect sleep diseases from non-invasive sensors.
Sleep study can be used for detection of sleep quality and in general bed behaviors. These results can helpful for regulating sleep and recognizing different sleeping disorders of human. In comparison to the leading standard measuring system, which is Polysomnography (PSG), the system proposed in this work is a non-invasive sleep monitoring device. For continuous analysis or home use, the PSG or wearable Actigraphy devices tends to be uncomfortable. Besides, these methods not only decrease practicality due to the process of having to put them on, but they are also very expensive. The system proposed in this paper classifies respiration and body movement with only one type of sensor and also in a noninvasive way. The sensor used is a pressure sensor. This sensor is low cost and can be used for commercial proposes. The system was tested by carrying out an experiment that recorded the sleep process of a subject. These recordings showed excellent results in the classification of breathing rate and body movements.
Respiratory diseases are leading causes of death and disability in the world. The recent COVID-19 pandemic is also affecting the respiratory system. Detecting and diagnosing respiratory diseases requires both medical professionals and the clinical environment. Most of the techniques used up to date were also invasive or expensive.
Some research groups are developing hardware devices and techniques to make possible a non-invasive or even remote respiratory sound acquisition. These sounds are then processed and analysed for clinical, scientific, or educational purposes.
We present the literature review of non-invasive sound acquisition devices and techniques.
The results are about a huge number of digital tools, like microphones, wearables, or Internet of Thing devices, that can be used in this scope.
Some interesting applications have been found. Some devices make easier the sound acquisition in a clinic environment, but others make possible daily monitoring outside that ambient. We aim to use some of these devices and include the non-invasive recorded respiratory sounds in a Digital Twin system for personalized health.
Sleep analysis using a Polysomnography system is difficult and expensive. That is why we suggest a non-invasive and unobtrusive measurement. Very few people want the cables or devices attached to their bodies during sleep. The proposed approach is to implement a monitoring system, so the subject is not bothered. As a result, the idea is a non-invasive monitoring system based on detecting pressure distribution. This system should be able to measure the pressure differences that occur during a single heartbeat and during breathing through the mattress. The system consists of two blocks signal acquisition and signal processing. This whole technology should be economical to be affordable enough for every user. As a result, preprocessed data is obtained for further detailed analysis using different filters for heartbeat and respiration detection. In the initial stage of filtration, Butterworth filters are used.
Sleep is extremely important for physical and mental health. Although polysomnography is an established approach in sleep analysis, it is quite intrusive and expensive. Consequently, developing a non-invasive and non-intrusive home sleep monitoring system with minimal influence on patients, that can reliably and accurately measure cardiorespiratory parameters, is of great interest. The aim of this study is to validate a non-invasive and unobtrusive cardiorespiratory parameter monitoring system based on an accelerometer sensor. This system includes a special holder to install the system under the bed mattress. The additional aim is to determine the optimum relative system position (in relation to the subject) at which the most accurate and precise values of measured parameters could be achieved. The data were collected from 23 subjects (13 males and 10 females). The obtained ballistocardiogram signal was sequentially processed using a sixth-order Butterworth bandpass filter and a moving average filter. As a result, an average error (compared to reference values) of 2.24 beats per minute for heart rate and 1.52 breaths per minute for respiratory rate was achieved, regardless of the subject’s sleep position. For males and females, the errors were 2.28 bpm and 2.19 bpm for heart rate and 1.41 rpm and 1.30 rpm for respiratory rate. We determined that placing the sensor and system at chest level is the preferred configuration for cardiorespiratory measurement. Further studies of the system’s performance in larger groups of subjects are required, despite the promising results of the current tests in healthy subjects.
The present work proposes the use of modern ICT technologies such as smartphones, NFCs, internet, and web technologies, to help patients in carrying out their therapies. The implemented system provides a calendar with a reminder of the assumptions, ensures the drug identification through NFC, allows remote assistance from healthcare staff and family members to check and manage the therapy in real-time. The system also provides centralized information on the patient's therapeutic situation, helpful in choosing new compatible therapies.
The use of deep learning models with medical data is becoming more widespread. However, although numerous models have shown high accuracy in medical-related tasks, such as medical image recognition (e.g. radiographs), there are still many problems with seeing these models operating in a real healthcare environment. This article presents a series of basic requirements that must be taken into account when developing deep learning models for biomedical time series classification tasks, with the aim of facilitating the subsequent production of the models in healthcare. These requirements range from the correct collection of data, to the existing techniques for a correct explanation of the results obtained by the models. This is due to the fact that one of the main reasons why the use of deep learning models is not more widespread in healthcare settings is their lack of clarity when it comes to explaining decision making.
The evaluation of the effectiveness of different machine learning algorithms on a publicly available database of signals derived from wearable devices is presented with the goal of optimizing human activity recognition and classification. Among the wide number of body signals we choose a couple of signals, namely photoplethysmographic (optically detected subcutaneous blood volume) and tri-axis acceleration signals that are easy to be simultaneously acquired using commercial widespread devices (e.g. smartwatches) as well as custom wearable wireless devices designed for sport, healthcare, or clinical purposes. To this end, two widely used algorithms (decision tree and k-nearest neighbor) were tested, and their performance were compared to two new recent algorithms (particle Bernstein and a Monte Carlo-based regression) both in terms of accuracy and processing time. A data preprocessing phase was also considered to improve the performance of the machine learning procedures, in order to reduce the problem size and a detailed analysis of the compression strategy and results is also presented.
In recent decades, it can be observed that a steady increase in the volume of tourism is a stable trend. To offer travel opportunities to all groups, it is also necessary to prepare offers for people in need of long-term care or people with disabilities. One of the ways to improve accessibility could be digital technologies, which could help in planning as well as in carrying out trips. In the work presented, a study of barriers was first conducted, which led to selecting technologies for a test setup after analysis. The main focus was on a mobile app with travel information and 360° tours. The evaluation results showed that both technologies could increase accessibility, but some essential aspects (such as usability, completeness, relevance, etc.) need to be considered when implementing them.
Sleep is a multi-dimensional influencing factor on physical health, cognitive function, emotional well-being, mental health, daily performance, and productivity. The barriers such as time-consuming, invasiveness, and expense have caused a gradual shift in sleep monitoring from traditional and standard in-lab approach, e. g., polysomnography (PSG) to unobtrusive and noninvasive in-home sleep monitoring, yet further improvement is required. Despite an increasing interest in fiberoptic-based methods for cardiorespiratory estimation, the traditional mechanical-based sensors consist of force-sensitive resistors (FSR), lead zirconate titanate piezoelectric (PZT), and accelerometers yet serve as the dominant approach. The part of popularity lies in reducing the system’s complexity, expense, easy maintenance, and user-friendliness. However, care must be taken regarding the performance of such sensors with respect to accuracy and calibration.
Healthy sleep is required for sufficient restoration of the human body and brain. Therefore, in the case of sleep disorders, appropriate therapy should be applied timely, which requires a prompt diagnosis. Traditionally, a sleep diary is a part of diagnosis and therapy monitoring for some sleep disorders, such as cognitive behaviour therapy for insomnia. To automatise sleep monitoring and make it more comfortable for users, substituting a sleep diary with a smartwatch measurement could be considered. With the aim of providing accurate results, a study with a total of 30 night recordings was conducted. Objective sleep measurement with a Samsung Galaxy Watch 4 was compared with a subjective approach (sleep diary), evaluating the four relevant sleep characteristics: time of getting asleep, wake up time, sleep efficiency (SE), and total sleep time (TST). The performed analysis has demonstrated that the median difference between both measurement approaches was equal to 7 and 3 minutes for a time of getting asleep and wake up time correspondingly, which allows substituting a subjective measurement with a smartwatch. The SE was determined with a median difference between the two measurement methods of 5.22%. This result also implicates a possibility of substitution. Some single recordings have indicated a higher variance between the two approaches. Therefore, the conclusion can be made that a substitution provides reliable results primarily in the case of long-term monitoring. The results of the evaluation of the TST measurement do not allow to recommend substitution of the measurement method.
The exposure to the light has a great influence on human beings in their everyday life. Various lighting sources produce light that reaches the human eye and influences a rhythmic release of melatonin hormone, that is a sleep promoting factor.
Since the development of new technologies provides more control over illuminance, this work uses an IoT based lighting system to set up dim and bright scenarios. A small study has been performed on the influence of illuminance on sleep latency. The system consists of different light bulbs, sensors and a central bridge which are interconnected like a mesh network. Also, a mobile app has been developed, that allows to adjust the lighting in various rooms. With the help of a ferro-electret sensor, like applied in sleep monitoring systems, a subject’s sleep was monitored. The sensor is placed below the mattress and it collects data, which is stored and processed in a cloud or in other alternative locations.
The research was conducted on healthy young subjects after being previously exposed to the preconfigured illuminance for at least three hours before bedtime. The results indicate correlation between sleep onset latency and exposure to different illuminance before bedtime. In a dimmed environment, the subject fell asleep in average 28% faster compared to the brighter environment.
The massive use of patient data for the training of artificial intelligence algorithms is common nowadays in medicine. In this scientific work, a statistical analysis of one of the most used datasets for the training of artificial intelligence models for the detection of sleep disorders is performed: sleep health heart study 2. This study focuses on determining whether the gender and age of the patients have a relevant influence to consider working with differentiated datasets based on these variables for the training of artificial intelligence models.
Apnea is a sleep disorder characterized by breathing interruptions during sleep, impacting cardiorespiratory function and overall health. Traditional diagnostic methods, like polysomnography (PSG), are unobtrusive, leading to noninvasive monitoring. This study aims to develop and validate a novel sleep monitoring system using noninvasive sensor technology to estimate cardiorespiratory parameters and detect sleep apnea. We designed a seamless monitoring system integrating noncontact force-sensitive resistor sensors to collect ballistocardiogram signals associated with cardiorespiratory activity. We enhanced the sensor’s sensitivity and reduced the noise by designing a new concept of edge-measuring sensor using a hemisphere dome and mechanical hanger to distribute the force and mechanically amplify the micromovement caused by cardiac and respiration activities. In total, we deployed three edge-measuring sensors, two deployed under the thoracic and one under the abdominal regions. The system is supported with onboard signal preprocessing in multiple physical layers deployed under the mattress. We collected the data in four sleeping positions from 16 subjects and analyzed them using ensemble empirical mode decomposition (EMD) to avoid frequency mixing. We also developed an adaptive thresholding method to identify sleep apnea. The error was reduced to 3.98 and 1.43 beats/min (BPM) in heart rate (HR) and respiration estimation, respectively. The apnea was detected with an accuracy of 87%. We optimized the system such that only one edge-measuring sensor can measure the cardiorespiratory parameters. Such a reduction in the complexity and simplification of the instruction of use shows excellent potential for in-home and continuous monitoring.
Measuring cardiorespiratory parameters in sleep, using non-contact sensors and the Ballistocardiography technique has received much attention due to the low-cost, unobtrusive, and non-invasive method. Designing a user-friendly, simple-to-use, and easy-to-deployment preserving less errorprone remains open and challenging due to the complex morphology of the signal. In this work, using four forcesensitive resistor sensors, we conducted a study by designing four distributions of sensors, in order to simplify the complexity of the system by identifying the region of interest for heartbeat and respiration measurement. The sensors are deployed under the mattress and attached to the bed frame without any interference with the subjects. The four distributions are combined in two linear horizontal, one linear vertical, and one square, covering the influencing region in cardiorespiratory activities. We recruited 4 subjects and acquired data in four regular sleeping positions, each for a duration of 80 seconds. The signal processing was performed using discrete wavelet transform bior 3.9 and smooth level of 4 as well as bandpass filtering. The results indicate that we have achieved the mean absolute error of 2.35 and 4.34 for respiration and heartbeat, respectively. The results recommend the efficiency of a triangleshaped structure of three sensors for measuring heartbeat and respiration parameters in all four regular sleeping positions.