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The actual task of electrocardiographic examinations is to increase the reliability of diagnosing the condition of the heart. Within the framework of this task, an important direction is the solution of the inverse problem of electrocardiography, based on the processing of electrocardiographic signals of multichannel cardio leads at known electrode coordinates in these leads (Titomir et al. Noninvasiv electrocardiotopography, 2003), (Macfarlane et al. Comprehensive Electrocardiology, 2nd ed. (Chapter 9), 2011).
We consider the problem of increasing the informative value of electrocardiographic (ECG) surveys using data from multichannel electrocardiographic leads, that include both recorded electrocardiosignals and the coordinates of the electrodes placed on the surface of the human torso. In this area, we were interested in reconstruction of the surface distribution of the equivalent sources during the cardiac cycle at relatively low hardware cost. In our work, we propose to reconstruct the equivalent electrical sources by numerical methods, based on integral connection between the density of electrical sources and potential in a conductive medium. We consider maps of distributions of equivalent electric sources on the heart surface (HSSM), presenting source distributions in the form of a simple or double electrical layer. We indicate the dynamics of the heart electrical activity by the space-time mapping of equivalent electrical sources in HSSM.
There have been substantial research efforts for algorithms to improve continuous and automated assessment of various health-related questions in recent years. This paper addresses the deployment gap between those improving algorithms and their usability in care and mobile health applications. In practice, most algorithms require significant and founded technical knowledge to be deployed at home or support healthcare professionals. Therefore, the digital participation of persons in need of health care professionals lacks a usable interface to use the current technological advances. In this paper, we propose applying algorithms taken from research as web-based microservices following the common approach of a RESTful service to bridge the gap and make algorithms accessible to caregivers and patients without technical knowledge and extended hardware capabilities. We address implementation details, interpretation and realization of guidelines, and privacy concerns using our self-implemented example. Also, we address further usability guidelines and our approach to those.
This paper presents a generic method to enhance performance and incorporate temporal information for cardiorespiratory-based sleep stage classification with a limited feature set and limited data. The classification algorithm relies on random forests and a feature set extracted from long-time home monitoring for sleep analysis. Employing temporal feature stacking, the system could be significantly improved in terms of Cohen’s κ and accuracy. The detection performance could be improved for three classes of sleep stages (Wake, REM, Non-REM sleep), four classes (Wake, Non-REM-Light sleep, Non-REM Deep sleep, REM sleep), and five classes (Wake, N1, N2, N3/4, REM sleep) from a κ of 0.44 to 0.58, 0.33 to 0.51, and 0.28 to 0.44 respectively by stacking features before and after the epoch to be classified. Further analysis was done for the optimal length and combination method for this stacking approach. Overall, three methods and a variable duration between 30 s and 30 min have been analyzed. Overnight recordings of 36 healthy subjects from the Interdisciplinary Center for Sleep Medicine at Charité-Universitätsmedizin Berlin and Leave-One-Out-Cross-Validation on a patient-level have been used to validate the method.
A residual neural network was adapted and applied to the Physionet/Computing data in Cardiology Challenge 2020 to detect 24 different classes of cardiac abnormalities from 12-lead. Additive Gaussian noise, signal shifting, and the classification of signal sections of different lengths were applied to prevent the network from overfitting and facilitating generalization. Due to the use of a global pooling layer after the feature extractor, the network is independent of the signal’s length. On the hidden test set of the challenge, the model achieved a validation score of 0.656 and a full test score of 0.27, placing us 15th out of 41 officially ranked teams (Team name: UC_Lab_Kn). These results show the potential of deep neural networks for ap- plication to raw data and a complex multi-class multi-label classification problem, even if the training data is from di- verse datasets and of differing lengths.
Healthy and good sleep is a prerequisite for a rested mind and body. Both form the basis for physical and mental health. Healthy sleep is hindered by sleep disorders, the medically diagnosed frequency of which increases sharply from the age of 40. This chapter describes the formal specification of an on-course practical implementation for a non-invasive system based on biomedical signal processing to support the diagnosis and treatment of sleep-related diseases. The system aims to continuously monitor vital data during sleep in a patient’s home environment over long periods by using non-invasive technologies. At the center of the development is the MORPHEUS Box (MoBo), which consists of five main conceptualizations: the MoBo core, the MoBo-HW, the MoBo algorithm, the MoBo API, and the MoBo app. These synergistic elements aim to support the diagnosis and treatment of sleep-related diseases. Although there are related developments in individual aspects concerning the system, no comparative approach is known that gives a similar scope of functionality, deployment flexibility, extensibility, or the possibility to use multiple user groups. With the specification provided in this chapter, the MORPHEUS project sets a good platform, data model, and transmission strategies to bring an innovative proposal to measure sleep quality and detect sleep diseases from non-invasive sensors.
Nowadays there is a rich diversity of sleep monitoring systems available on the market. They promise to offer information about sleep quality of the user by recording a limited number of vital signals, mainly heart rate and body movement. Typically, fitness trackers, smart watches, smart shirts, smartphone applications or patches do not provide access to the raw sensor data. Moreover, the sleep classification algorithm and the agreement ratio with the gold standard, polysomnography (PSG) are not disclosed. Some commercial systems record and store the data on the wearable device, but the user needs to transfer and import it into specialised software applications or return it to the doctor, for clinical evaluation of the data set. Thus an immediate feedback mechanism or the possibility of remote control and supervision are lacking. Furthermore, many such systems only distinguish between sleep and wake states, or between wake, light sleep and deep sleep. It is not always clear how these stages are mapped to the four known sleep stages: REM, NREM1, NREM2, NREM3-4. [1] The goal of this research is to find a reduced complexity method to process a minimum number of bio vital signals, while providing accurate sleep classification results. The model we propose offers remote control and real time supervision capabilities, by using Internet of Things (IoT) technology. This paper focuses on the data processing method and the sleep classification logic. The body sensor network representing our data acquisition system will be described in a separate publication. Our solution showed promising results and a good potential to overcome the limitations of existing products. Further improvements will be made and subjects with different age and health conditions will be tested.
Development of an expert system to overpass citizens technological barriers on smart home and living
(2023)
Adopting new technologies can be overwhelming, even for people with experience in the field. For the general public, learning about new implementations, releases, brands, and enhancements can cause them to lose interest. There is a clear need to create point sources and platforms that provide helpful information about the novel and smart technologies, assisting users, technicians, and providers with products and technologies. The purpose of these platforms is twofold, as they can gather and share information on interests common to manufacturers and vendors. This paper presents the ”Finde-Dein-SmartHome” tool. Developed in association with the Smart Home & Living competence center [5] to help users learn about, understand, and purchase available technologies that meet their home automation needs. This tool aims to lower the usability barrier and guide potential customers to clear their doubts about privacy and pricing. Communities can use the information provided by this tool to identify market trends that could eventually lower costs for providers and incentivize access to innovative home technologies and devices supporting long-term care.
This paper compares two popular scripting implementations for hardware prototyping: Python scripts exe- cut from User-Space and C-based Linux-Driver processes executed from Kernel-Space, which can provide information to researchers when considering one or another in their implementations. Conclusions exhibit that deploying software scripts in the kernel space makes it possible to grant a certain quality of sensor information using a Raspberry Pi without the need for advanced real-time operational systems.
Respiratory diseases are leading causes of death and disability in the world. The recent COVID-19 pandemic is also affecting the respiratory system. Detecting and diagnosing respiratory diseases requires both medical professionals and the clinical environment. Most of the techniques used up to date were also invasive or expensive.
Some research groups are developing hardware devices and techniques to make possible a non-invasive or even remote respiratory sound acquisition. These sounds are then processed and analysed for clinical, scientific, or educational purposes.
We present the literature review of non-invasive sound acquisition devices and techniques.
The results are about a huge number of digital tools, like microphones, wearables, or Internet of Thing devices, that can be used in this scope.
Some interesting applications have been found. Some devices make easier the sound acquisition in a clinic environment, but others make possible daily monitoring outside that ambient. We aim to use some of these devices and include the non-invasive recorded respiratory sounds in a Digital Twin system for personalized health.
This paper presents the implementation of deep learning methods for sleep stage detection by using three signals that can be measured in a non-invasive way: heartbeat signal, respiratory signal, and movement signal. Since signals are measurements taken during the time, the problem is seen as time-series data classification. Deep learning methods are chosen to solve the problem are convolutional neural network and long-short term memory network. Input data is structured as a time-series sequence of mentioned signals that represent 30 seconds epoch, which is a standard interval for sleep analysis. The records used belong to the overall 23 subjects, which are divided into two subsets. Records from 18 subjects were used for training the data and from 5 subjects for testing the data. For detecting four sleep stages: REM (Rapid Eye Movement), Wake, Light sleep (Stage 1 and Stage 2), and Deep sleep (Stage 3 and Stage 4), the accuracy of the model is 55%, and F1 score is 44%. For five stages: REM, Stage 1, Stage 2, Deep sleep (Stage 3 and 4), and Wake, the model gives an accuracy of 40% and F1 score of 37%.
With the advancement in sensor technology and the trend shift of health measurement from treatment after diagnosis to abnormalities detection long before the occurrence, the approach of turning private spaces into diagnostic spaces has gained much attention. In this work, we designed and implemented a low-cost and compact form factor module that can be deployed on the steering wheel of cars as well as most frequently touch objects at home in order to measure physiological signals from the fingertip of the subject as well as environmental parameters. We estimated the heart rate and SpO2 with the error of 2.83 bpm and 3.52%, respectively. The signal evaluation of skin temperature shows a promising output with respect to environmental recalibration. In addition, the electrodermal activity sensor followed the reference signal, appropriately which indicates the potential for further development and application in stress measurement.
This work is a study about a comparison of survey tools and it should help developers in selecting a suited tool for application in an AAL environment. The first step was to identify the basic required functionality of the survey tools used for AAL technologies and to compare these tools by their functionality and assignments. The comparative study was derived from the data obtained, previous literature studies and further technical data. A list of requirements was stated and ordered in terms of relevance to the target application domain. With the help of an integrated assessment method, the calculation of a generalized estimate value was performed and the result is explained. Finally, the planned application of this tool in a running project is explained.
Ballistocardiography (BCG) can be used to monitor heart rate activity. Besides, the accelerometer should have high sensitivity and minimal internal noise; a low-cost approach was taken into consideration. Several measurements have been executed to determine the optimal positioning of a sensor under the mattress to obtain a signal strong enough for further analysis. A prototype for an unobtrusive accelerometer-based measurement system has been developed and tested in a conventional bed without any specific extras. The influence of the human sleep position for the output accelerometer data was tested. The obtained results indicate the potential to capture BCG signals using accelerometers. The measurement system can detect heart rate in an unobtrusive form in the home environment.
The digital twin concept has been widely known for asset monitoring in the industry for a long time. A clear example is the automotive industry. Recently, there has also been significant interest in the application of digital twins in healthcare, especially in genomics in what is known as precision medicine. This work focuses on another medical speciality where digital twins can be applied, sleep medicine. However, there is still great controversy about the fundamentals that constitute digital twins, such as what this concept is based on and how it can be included in healthcare effectively and sustainably. This article reviews digital twins and their role so far in what is known as personalized medicine. In addition, a series of steps will be exposed for a possible implementation of a digital twin for a patient suffering from sleep disorders. For this, artificial intelligence techniques, clinical data management, and possible solutions for explaining the results derived from artificial intelligence models will be addressed.
The use of deep learning models with medical data is becoming more widespread. However, although numerous models have shown high accuracy in medical-related tasks, such as medical image recognition (e.g. radiographs), there are still many problems with seeing these models operating in a real healthcare environment. This article presents a series of basic requirements that must be taken into account when developing deep learning models for biomedical time series classification tasks, with the aim of facilitating the subsequent production of the models in healthcare. These requirements range from the correct collection of data, to the existing techniques for a correct explanation of the results obtained by the models. This is due to the fact that one of the main reasons why the use of deep learning models is not more widespread in healthcare settings is their lack of clarity when it comes to explaining decision making.
oday many scientific works are using deep learning algorithms and time series, which can detect physiological events of interest. In sleep medicine, this is particularly relevant in detecting sleep apnea, specifically in detecting obstructive sleep apnea events. Deep learning algorithms with different architectures are used to achieve decent results in accuracy, sensitivity, etc. Although there are models that can reliably determine apnea and hypopnea events, another essential aspect to consider is the explainability of these models, i.e., why a model makes a particular decision. Another critical factor is how these deep learning models determine how severe obstructive sleep apnea is in patients based on the apnea-hypopnea index (AHI). Deep learning models trained by two approaches for AHI determination are exposed in this work. Approaches vary depending on the data format the models are fed: full-time series and window-based time series.
Background: Polysomnography (PSG) is the gold standard for detecting obstructive sleep apnea (OSA). However, this technique has many disadvantages when using it outside the hospital or for daily use. Portable monitors (PMs) aim to streamline the OSA detection process through deep learning (DL).
Materials and methods: We studied how to detect OSA events and calculate the apnea-hypopnea index (AHI) by using deep learning models that aim to be implemented on PMs. Several deep learning models are presented after being trained on polysomnography data from the National Sleep Research Resource (NSRR) repository. The best hyperparameters for the DL architecture are presented. In addition, emphasis is focused on model explainability techniques, concretely on Gradient-weighted Class Activation Mapping (Grad-CAM).
Results: The results for the best DL model are presented and analyzed. The interpretability of the DL model is also analyzed by studying the regions of the signals that are most relevant for the model to make the decision. The model that yields the best result is a one-dimensional convolutional neural network (1D-CNN) with 84.3% accuracy.
Conclusion: The use of PMs using machine learning techniques for detecting OSA events still has a long way to go. However, our method for developing explainable DL models demonstrates that PMs appear to be a promising alternative to PSG in the future for the detection of obstructive apnea events and the automatic calculation of AHI.
Introduction. Despite its high accuracy, polysomnography (PSG) has several drawbacks for diagnosing obstructive sleep apnea (OSA). Consequently, multiple portable monitors (PMs) have been proposed. Objective. This systematic review aims to investigate the current literature to analyze the sets of physiological parameters captured by a PM to select the minimum number of such physiological signals while maintaining accurate results in OSA detection. Methods. Inclusion and exclusion criteria for the selection of publications were established prior to the search. The evaluation of the publications was made based on one central question and several specific questions. Results. The abilities to detect hypopneas, sleep time, or awakenings were some of the features studied to investigate the full functionality of the PMs to select the most relevant set of physiological signals. Based on the physiological parameters collected (one to six), the PMs were classified into sets according to the level of evidence. The advantages and the disadvantages of each possible set of signals were explained by answering the research questions proposed in the methods. Conclusions. The minimum number of physiological signals detected by PMs for the detection of OSA depends mainly on the purpose and context of the sleep study. The set of three physiological signals showed the best results in the detection of OSA.
The massive use of patient data for the training of artificial intelligence algorithms is common nowadays in medicine. In this scientific work, a statistical analysis of one of the most used datasets for the training of artificial intelligence models for the detection of sleep disorders is performed: sleep health heart study 2. This study focuses on determining whether the gender and age of the patients have a relevant influence to consider working with differentiated datasets based on these variables for the training of artificial intelligence models.
The development of automatic solutions for the detection of physiological events of interest is booming. Improvements in the collection and storage of large amounts of healthcare data allow access to these data faster and more efficiently. This fact means that the development of artificial intelligence models for the detection and monitoring of a large number of pathologies is becoming increasingly common in the medical field. In particular, developing deep learning models for detecting obstructive apnea (OSA) events is at the forefront. Numerous scientific studies focus on the architecture of the models and the results that these models can provide in terms of OSA classification and Apnea-Hypopnea-Index (AHI) calculation. However, little focus is put on other aspects of great relevance that are crucial for the training and performance of the models. Among these aspects can be found the set of physiological signals used and the preprocessing tasks prior to model training. This paper covers the essential requirements that must be considered before training the deep learning model for obstructive sleep apnea detection, in addition to covering solutions that currently exist in the scientific literature by analyzing the preprocessing tasks prior to training.
In diesem Beitrag wird eine Methode des maschinellen Lernens entwickelt, die die Schlafstadienerkennung untersucht. Übliche Methoden der Schlafanalyse basieren auf der Polysomnographie (PSG). Der präsentierte Ansatz basiert auf Signalen, die ausschließlich nicht-invasiv in einer häuslichen Umgebung gemessen werden können. Bewegungs-, Herzschlags- und Atmungssignale können vergleichsweise leicht erfasst werden aber die Erkennung der Schlafstadien ist dadurch erschwert. Die Signale werden als Zeitreihenfolge strukturiert und in Epochen überführt. Die Leistungsfähigkeit von maschinellem Lernen wird der Polysomnographie gegenübergestellt und bewertet.
The citizen-centered health platform project is intended to provide a platform that can be used in EU cross-border regions, where social and economic exchange occurs across national borders. The overriding challenges are: (a) social: improving citizen-centered health and care provision; (b) technical: providing a digital platform for networking citizens, service providers, and municipal actors; (c) economic: developing long-term successful (sustainable) business models/value chains. The platform should strengthen and expand existing networks and establish new regional networks. Each network addresses particular challenges and apply them in a region-specific manner. Here, the national boundary conditions and the interregional needs play an essential role. These objectives require sufficient participation of civil society representatives. Furthermore, the platform will establish an overarching, sustainable, and knowledge-based network of health experts. The platform is to be jointly developed and implemented in the regions and follow an open-access approach. Therefore, synergies will be shared more quickly, strengthening competencies and competitiveness. In addition to practice partners, scientific and municipal institutions and SMEs are involved. The actors thus contribute to scientific performance, innovative strength, and resilience.
Autism spectrum disorders (ASD) affect a large number of children both in the Russian Federation and in Germany. Early diagnosis is key for these children, because the sooner parents notice such disorders in a child and the rehabilitation and treatment program starts, the higher the likelihood of his social adaptation. The difficulties in raising such a child lie in the complexity of his learning outside of children's groups and the complexity of his medical care. In this regard, the development of digital applications that facilitate medical care and education of such children at home is important and relevant. The purpose of the project is to improve the availability and quality of healthcare and social adaptation at home of children with ASD through the use of digital technologies.
Sleep is a multi-dimensional influencing factor on physical health, cognitive function, emotional well-being, mental health, daily performance, and productivity. The barriers such as time-consuming, invasiveness, and expense have caused a gradual shift in sleep monitoring from traditional and standard in-lab approach, e. g., polysomnography (PSG) to unobtrusive and noninvasive in-home sleep monitoring, yet further improvement is required. Despite an increasing interest in fiberoptic-based methods for cardiorespiratory estimation, the traditional mechanical-based sensors consist of force-sensitive resistors (FSR), lead zirconate titanate piezoelectric (PZT), and accelerometers yet serve as the dominant approach. The part of popularity lies in reducing the system’s complexity, expense, easy maintenance, and user-friendliness. However, care must be taken regarding the performance of such sensors with respect to accuracy and calibration.
The development of home health systems can provide continuous and user-friendly monitoring of key health parameters. This project aims to create a concept for such a system, implement it on a test basis, and evaluate it. Three health areas were selected for this purpose:
Sleep, Stress, and Rehabilitation. Appropriate devices were installed in the homes of test subjects and used by them for two weeks. Besides, relevant questionnaires were completed to obtain a complete picture. Finally, the implemented system was evaluated, and the results of the conducted study showed that home health systems have great potential. However, it is necessary to consider some points to increase the usability of the system and the motivation of the users. Among others, ease of use of the equipment is of extreme importance.
Long-term sleep monitoring can be done primarily in the home environment. Good patient acceptance requires low user and installation barriers. The selection of parameters in this approach is significantly limited compared to a PSG session. The aim is a qualified selection of parameters, which on the one hand allow a sufficiently good classification of sleep phases and on the other hand can be detected by non-invasive methods.
The goal of the presented project is to develop the concept of home ehealth centers for barrier-free and cross-border telemedicine. AAL technologies are already present on the market but there is still a gap to close until they can be used for ordinary patient needs. The general idea needs to be accompanied by new services, which should be brought together in order to provide a full coverage of service for the users. Sleep and stress were chosen as predominant diseases for a detailed study within this project because of their widespread influence in the population. The executed scientific study of available home devices analyzing sleep has provided the necessary to select appropriate devices. The first choice for the project implementation is the device EMFIT QS+. This equipment provides a part of a complete system that a home telemedical hospital can provide at a level of precision and communication with internal and/or external health services.
Assistive environments are entering our homes faster than ever. However, there are still various barriers to be broken. One of the crucial points is a personalization of offered services and integration of assistive technologies in common objects and therefore in a regular daily routine. Recognition of sleep patterns for the preliminary sleep study is one of the health services that could be performed in an undisturbing way. This article proposes the hardware system for the measurement of bio-vital signals necessary for initial sleep study in a non-obtrusive way. The first results confirm the potential of measurement of breathing and movement signals with the proposed system.
Present demographic change and a growing population of elderly people leads to new medical needs. Meeting these with state of the art technology is as a consequence a rapidly growing market. So this work is aimed at taking modern concepts of mobile and sensor technology and putting them in a medical context. By measuring a user’s vital signs on sensors which are processed on a Android smartphone, the target system is able to determine the current health state of the user and to visualize gathered information. The system also includes a weather forecasting functionality, which alerts the user on possibly dangerous future meteorological events. All information are collected centrally and distributed to users based on their location. Further, the system can correlate the client-side measurement of vital signs with a server-side weather history. This enables personalized forecasting for each user individually. Finally, a portable and affordable application was developed that continuously monitors the health status by many vital sensors, all united on a common smartphone.
Für die Überwachung des Schlafs zu Hause sind nichtinvasive Methoden besonders gut anwendbar. Die Signale, die häufig überwacht werden, sind Herzfrequenz und Atemfrequenz. Die Ballistokardiographie (BCG)ist eine Technik, bei der die Herzfrequenz aus den mechanischen Schwingungen des Körpers bei jedem Herzzyklus gemessen wird. Kürzlich wurden Übersichtsarbeiten veröffentlicht. Die Untersuchung soll in einem ersten Ansatz bewerten, ob die Herzfrequenz anhand von BCG erkannt werden kann. Die wesentlichen Randbedingungen sind, ob dies gelingt, wenn der Sensor unter der Matratze positioniert wird und kostengünstige Sensoren zum Einsatz kommen.
Measuring cardiorespiratory parameters in sleep, using non-contact sensors and the Ballistocardiography technique has received much attention due to the low-cost, unobtrusive, and non-invasive method. Designing a user-friendly, simple-to-use, and easy-to-deployment preserving less errorprone remains open and challenging due to the complex morphology of the signal. In this work, using four forcesensitive resistor sensors, we conducted a study by designing four distributions of sensors, in order to simplify the complexity of the system by identifying the region of interest for heartbeat and respiration measurement. The sensors are deployed under the mattress and attached to the bed frame without any interference with the subjects. The four distributions are combined in two linear horizontal, one linear vertical, and one square, covering the influencing region in cardiorespiratory activities. We recruited 4 subjects and acquired data in four regular sleeping positions, each for a duration of 80 seconds. The signal processing was performed using discrete wavelet transform bior 3.9 and smooth level of 4 as well as bandpass filtering. The results indicate that we have achieved the mean absolute error of 2.35 and 4.34 for respiration and heartbeat, respectively. The results recommend the efficiency of a triangleshaped structure of three sensors for measuring heartbeat and respiration parameters in all four regular sleeping positions.
Stress is a recognized as a predominant disease with growing costs of treatment. The approach presented here is aimed to detect stress using a light weighted, mobile, cheap and easy to use system. The result shows that stress can be detected even in case a person’s natural bio vital data is out of the main range. The system enables storage of measured data, while maintaining communication channels of online and post-processing.
The principal objective of this study is to investigate the impact of perceived stress on traffic and road safety. Therefore, we designed a study that allows the generation and collection of stress-relevant data. Drivers often experience stress due to their perception of lack of control during the driving process. This can lead to an increased likelihood of traffic accidents, driver errors, and traffic violations. To explore this phenomenon, we used the Stress Perceived Questionnaire (PSQ) to evaluate perceived stress levels during driving simulations and the EPQR questionnaire to determine the personality of the driver. With the presented study, participants can categorised based on their emotional stability and personality traits. Wearable devices were utilised to monitor each participant's instantaneous heart rate (HR) due to their non-intrusive and portable nature. The findings of this study deliver an overview of the link between stress and traffic and road safety. These findings can be utilised for future research and implementing strategies to reduce road accidents and promote traffic safety.
The purpose of this paper is to examine the effects of perceived stress on traffic and road safety. One of the leading causes of stress among drivers is the feeling of having a lack of control during the driving process. Stress can result in more traffic accidents, an increase in driver errors, and an increase in traffic violations. To study this phenomenon, the Stress Perceived Questionnaire (PSQ) was used to evaluate the perceived stress while driving in a simulation. The study was conducted with participants from Germany, and they were grouped into different categories based on their emotional stability. Each participant was monitored using wearable devices that measured their instantaneous heart rate (HR). The preference for wearable devices was due to their non-intrusive and portable nature. The results of this study provide an overview of how stress can affect traffic and road safety, which can be used for future research or to implement strategies to reduce road accidents and promote traffic safety.
Methods based exclusively on heart rate hardly allow to differentiate between physical activity, stress, relaxation, and rest, that is why an additional sensor like activity/movement sensor added for detection and classification. The response of the heart to physical activity, stress, relaxation, and no activity can be very similar. In this study, we can observe the influence of induced stress and analyze which metrics could be considered for its detection. The changes in the Root Mean Square of the Successive Differences provide us with information about physiological changes. A set of measurements collecting the RR intervals was taken. The intervals are used as a parameter to distinguish four different stages. Parameters like skin conductivity or skin temperature were not used because the main aim is to maintain a minimum number of sensors and devices and thereby to increase the wearability in the future.
The investigation of stress requires to distinguish between stress caused by physical activity and stress that is caused by psychosocial factors. The behaviour of the heart in response to stress and physical activity is very similar in case the set of monitored parameters is reduced to one. Currently, the differentiation remains difficult and methods which only use the heart rate are not able to differentiate between stress and physical activity, without using additional sensor data input. The approach focusses on methods which generate signals providing characteristics that are useful for detecting stress, physical activity, no activity and relaxation.
The perception of the amount of stress is subjective to every person, and the perception of it changes depending on many factors. One of the factors that has an impact on perceived stress is the emotional state. In this work, we compare the emotional state of 40 German driving students and present different partitions that can be advantageous for using artificial intelligence and classification. Like this, we evaluate the data quality and prepare for the specific use. The Stress Perceived Questionnaire (PSQ20) was employed to assess the level of stress experienced by individuals while participating in a driving simulation for 5 and 25 min. As a result of our analysis, we present a categorisation of various emotional states into intervals, comparing different classifications and facilitating a more straightforward implementation of artificial intelligence for classification purposes.
Stress is recognized as a predominant disease with raising costs for rehabilitation and treatment. Currently there several different approaches that can be used for determining and calculating the stress levels. Usually the methods for determining stress are divided in two categories. The first category do not require any special equipment for measuring the stress. This category useless the variation in the behaviour patterns that occur while stress. The core disadvantage for the category is their limitation to specific use case. The second category uses laboratories instruments and biological sensors. This category allow to measure stress precisely and proficiently but on the same time they are not mobile and transportable and do not support real-time feedback. This work presents a mobile system that provides the calculation of stress. For achieving this, the of a mobile ECG sensor is analysed, processed and visualised over a mobile system like a smartphone. This work also explains the used stress measurement algorithm. The result of this work is a portable system that can be used with a mobile system like a smartphone as visual interface for reporting the current stress level.
Stress and physical activities are important aspects of life of people. Body reactions on stress and on physical activities can be very similar but long-term stress leads to diseases and damages the body. Currently there is no method to differentiate easily and clearly between these two aspects in a time slot. We have confronted this problem while developing a mobile system for detection and analysis of stress. This paper presents an approach, which uses a long-term monitor with ECG/EKG capabilities and analysis of the heart rate data that is extracted from the device. The focus of the work is to find characteristics that are useful for differentiation between physical activity and stress.
Stress is recognized as a factor of predominant disease and in the future the costs for treatment will increase. The presented approach tries to detect stress in a very basic and easy to implement way, so that the cost for the device and effort to wear it remain low. The user should benefit from the fact that the system offers an easy interface reporting the status of his body in real time. In parallel, the system provides interfaces to pass the obtained data forward for further processing and (professional) analyses, in case the user agrees. The system is designed to be used in every day’s activities and it is not restricted to laboratory use or environments. The implementation of the enhanced prototype shows that the detection of stress and the reporting can be managed using correlation plots and automatic pattern recognition even on a very light-weighted microcontroller platform.
To evaluate the quality of sleep, it is important to determine how much time was spent in each sleep stage during the night. The gold standard in this domain is an overnight polysomnography (PSG). But the recording of the necessary electrophysiological signals is extensive and complex and the environment of the sleep laboratory, which is unfamiliar to the patient, might lead to distorted results. In this paper, a sleep stage detection algorithm is proposed that uses only the heart rate signal, derived from electrocardiogram (ECG), as a discriminator. This would make it possible for sleep analysis to be performed at home, saving a lot of effort and money. From the heart rate, using the fast Fourier transformation (FFT), three parameters were calculated in order to distinguish between the different sleep stages. ECG data along with a hypnogram scored by professionals was used from Physionet database, making it easy to compare the results. With an agreement rate of 41.3%, this approach is a good foundation for future research.
In previous studies, we used a method for detecting stress that was based exclusively on heart rate and ECG for differentiation between such situations as mental stress, physical activity, relaxation, and rest. As a response of the heart to these situations, we observed different behavior in the Root Mean Square of the Successive differences heartbeats (RMSSD). This study aims to analyze Virtual Reality via a virtual reality headset as an effective stressor for future works. The value of the Root Mean Square of the Successive Differences is an important marker for the parasympathetic effector on the heart and can provide information about stress. For these measurements, the RR interval was collected using a breast belt. In these studies, we can observe the Root Mean Square of the successive differences heartbeats. Additional sensors for the analysis were not used. We conducted experiments with ten subjects that had to drive a simulator for 25 minutes using monitors and 25 minutes using virtual reality headset. Before starting and after finishing each simulation, the subjects had to complete a survey in which they had to describe their mental state. The experiment results show that driving using virtual reality headset has some influence on the heart rate and RMSSD, but it does not significantly increase the stress of driving.
While driving, stress is caused by situations in which the driver estimates their ability to manage the driving demands as insufficient or loses the capability to handle the situation. This leads to increased numbers of driver mistakes and traffic violations. Additional stressing factors are time pressure, road conditions, or dislike for driving. Therefore, stress affects driver and road safety. Stress is classified into two categories depending on its duration and the effects on the body and psyche: short-term eustress and constantly present distress, which causes degenerative effects. In this work, we focus on distress. Wearable sensors are handy tools for collecting biosignals like heart rate, activity, etc. Easy installation and non-intrusive nature make them convenient for calculating stress. This study focuses on the investigation of stress and its implications. Specifically, the research conducts an analysis of stress within a select group of individuals from both Spain and Germany. The primary objective is to examine the influence of recognized psychological factors, including personality traits such as neuroticism, extroversion, psychoticism, stress and road safety. The estimation of stress levels was accomplished through the collection of physiological parameters (R-R intervals) using a Polar H10 chest strap. We observed that personality traits, such as extroversion, exhibited similar trends during relaxation, with an average heart rate 6% higher in Spain and 3% higher in Germany. However, while driving, introverts, on average, experienced more stress, with rates 4% and 1% lower than extroverts in Spain and Germany, respectively.
Cardiovascular diseases are directly or indirectly responsible for up to 38.5% of all deaths in Germany and thus represent the most frequent cause of death. At present, heart diseases are mainly discovered by chance during routine visits to the doctor or when acute symptoms occur. However, there is no practical method to proactively detect diseases or abnormalities of the heart in the daily environment and to take preventive measures for the person concerned. Long-term ECG devices, as currently used by physicians, are simply too expensive, impractical, and not widely available for everyday use. This work aims to develop an ECG device suitable for everyday use that can be worn directly on the body. For this purpose, an already existing hardware platform will be analyzed, and the corresponding potential for improvement will be identified. A precise picture of the existing data quality is obtained by metrological examination, and corresponding requirements are defined. Based on these identified optimization potentials, a new ECG device is developed. The revised ECG device is characterized by a high integration density and combines all components directly on one board except the battery and the ECG electrodes. The compact design allows the device to be attached directly to the chest. An integrated microcontroller allows digital signal processing without the need for an additional computer. Central features of the evaluation are a peak detection for detecting R-peaks and a calculation of the current heart rate based on the RR interval. To ensure the validity of the detected R-peaks, a model of the anatomical conditions is used. Thus, unrealistic RR-intervals can be excluded. The wireless interface allows continuous transmission of the calculated heart rate. Following the development of hardware and software, the results are verified, and appropriate conclusions about the data quality are drawn. As a result, a very compact and wearable ECG device with different wireless technologies, data storage, and evaluation of RR intervals was developed. Some tests yelled runtimes up to 24 hours with wireless Lan activated and streaming.
The number of home office workers sitting for many hours is increasing. The sensor chair is tracking users’ sitting behavior which the help of pressure sensors and tries to avoid wrong postures which may cause diseases. The system provides live monitoring of the pressure distribution via web interface, as well as sitting posture prediction in real time. Posture analysis is realized through machine learning algorithm using a decision tree classifier that is compared to a random forest. Data acquisition and aggregation for the learning process happens with a mobile app adding users biometrical data and the taken sitting posture as label. The sensor chair is able to differentiate between an arched back, a neutral posture or a laid back position taken on the chair. The classifier achieves an accuracy of 97.4% on our test set and is comparable to the performance of the random forest with 98.9%.
A significant proportion of road traffic accidents are due to inattentiveness or fatigue at the wheel. Approaches to monitoring the driver's condition range from eye tracking and driving behavior analysis to yawn and blink detection and ECG measurement. This work describes the development of a mobile system for the measurement and processing of ECG data. The aim of the signal processing is to quantify the driver’s fatigue with the heartrate variability (HRV). The work includes the hardware and software design of the sensor. First, the development of low-noise electronics including AD conversion is described. Then the software signal processing with QRS complex detection and plotting front end is explained. The resulting sensor is compact, low-cost and provides a good signal for HRV extraction.
Sleep is an important part of our life that significantly influences our health and well-being. The monitoring of sleep can provide data based on which sleep quality could be improved. This paper presents a system for heart rate detection during sleep. The data is collected from sensors underneath the test subjects. Though the data contains noise, it needs to be filtered to remove it. Due to the low strength of the signals, they need to be amplified after filtering. At some points of the signal, particular heartbeats may not be tracked by sensors due to the failure of a sensor or other reasons, which should be considered. The heart rate is detected in intervals of 15 s. A tool is implemented that detects the heart rate and visualizes it. The preprocessing of the data is performed with several filters: a highpass filter, a band-reject filter, a lowpass filter, and a motion detector. After the preprocessing of the data, the quality of the signal is significantly increased, and detection is possible.
Deep Learning-based EEG Detection of Mental Alertness States from Drivers under Ethical Aspects
(2022)
One of the most critical factors for a successful road trip is a high degree of alertness while driving. Even a split second of inattention or sleepiness in a crucial moment, will make the difference between life and death. Several prestigious car manufacturers are currently pursuing the aim of automated drowsiness identification to resolve this problem. The path between neuro-scientific research in connection with artificial intelligence and the preservation of the dignity of human individual’s and its inviolability, is very narrow. The key contribution of this work is a system of data analysis for EEGs during a driving session, which draws on previous studies analyzing heart rate (ECG), brain waves (EEG), and eye function (EOG). The gathered data is hereby treated as sensitive as possible, taking ethical regulations into consideration. Obtaining evaluable signs of evolving exhaustion includes techniques that obtain sleeping stage frequencies, problematic are hereby the correlated interference’s in the signal. This research focuses on a processing chain for EEG band splitting that involves band-pass filtering, principal component analysis (PCA), independent component analysis (ICA) with automatic artefact severance, and fast fourier transformation (FFT). The classification is based on a step-by-step adaptive deep learning analysis that detects theta rhythms as a drowsiness predictor in the pre-processed data. It was possible to obtain an offline detection rate of 89% and an online detection rate of 73%. The method is linked to the simulated driving scenario for which it was developed. This leaves space for more optimization on laboratory methods and data collection during wakefulness-dependent operations.
The goal of this paper pretends to show how a bed system with an embedded system with sensor is able to analyze a person’s movement, breathing and recognizing the positions that the subject is lying on the bed during the night without any additional physical contact. The measurements are performed with sensors placed between the mattress and the frame. An Intel Edison board was used as an endpoint that served as a communication node from the mesh network to external service. Two nodes and Intel Edison are attached to the bottom of the bed frame and they are connected to the sensors.
The overall goal of this work is to detect and analyze a person's movement, breathing and heart rate during sleep in a common bed overnight without any additional physical contact. The measurement is performed with the help of
sensors placed between the mattress and the frame. A two-stage pattern classification algorithm based has been implemented that applies statistics analysis to recognize the position of patients. The system is implemented in a sensors-network, hosting several nodes and communication end-points to support quick and efficient classification. The overall tests show convincing results for the position recognition and a reasonable overlap in matching.
These days computer analysis of ECG (Electrocardiograms) signals is common. There are many real-time QRS recognition algorithms; one of these algorithms is Pan-Tompkins Algorithm. Which the Pan-Tompkins Algorithm can detect QRS complexes of ECG signals. The proposed algorithm is analysed the data stream of the heartbeat based on the digital analysis of the amplitude, the bandwidth, and the slope. In addition to that, the stress algorithm compares whether the current heartbeat is similar or different to the last heartbeat after detecting the ECG signals. This algorithm determines the stress detection for the patient on the real-time. In order to implement the new algorithm with higher performance, the parallel programming language CUDA is used. The algorithm determines stress at the same time by determining the RR interval. The algorithm uses a different function as beat detector and a beat classifier of stress.
The present work proposes the use of modern ICT technologies such as smartphones, NFCs, internet, and web technologies, to help patients in carrying out their therapies. The implemented system provides a calendar with a reminder of the assumptions, ensures the drug identification through NFC, allows remote assistance from healthcare staff and family members to check and manage the therapy in real-time. The system also provides centralized information on the patient's therapeutic situation, helpful in choosing new compatible therapies.
Preliminary results of homomorphic deconvolution application to surface EMG signals during walking
(2021)
Homomorphic deconvolution is applied to sEMG signals recorded during walking. Gastrocnemius lateralis and tibialis anterior signals were acquired according to SENIAM recommendation. MUAP parameters like amplitude and scale were estimated, whilst the MUAP shape parameter was fixed. This features a useful time-frequency representation of sEMG signal. Estimation of scale MUAP parameter was verified extracting the mean frequency of filtered EMG signal, extracted from the scale parameter estimated with two different MUAP shape values.
Unintrusive health monitoring systems is important when continuous monitoring of the patient vital signals is required. In this paper, signals obtained from accelerometers placed under a bed are processed with ballistocardiography algorithms and compared with synchronized electrocardiographic signals.
Autismus-Spektrum-Störungen (ASD) bei Kindern werden häufig zu spät diagnostiziert und die Begleitung der chronischen Krankheit gestaltet sich schwierig. Der vorgestellte Ansatz erlaubt die Behandlung der Kinder in dem bekannten häuslichen Umfeld und versucht die Beziehungen zwischen Schlaf und Verhalten herauszuarbeiten. Die gewonnenen Erkenntnisse sollen die Lebensqualität der Patienten verbessern und den Eltern Hilfestellung geben. Die notwendige infrastrukturelle Unterstützung wird durch medizinisches Fachpersonal geleistet, das auf einen web-basierten Service zurückgreifen kann, der sämtliche Prozesse (Diagnostik, Datenerfassung, -aufzeichnung und Training etc.) begleitet. Die anonymisierten Daten werden in einem Diagnosesystem zentral abgelegt und können so für zukünftige Behandlungsstrategien nutzbar sein. Die umfassende Lösung setzt auf zentrale Elemente von Smart-Homes und AAL auf.
Due to the rising need for palliative care in Russia, it is crucial to provide timely and high-quality solutions for patients, relatives, and caregivers. A methodology for remote monitoring of patients in need of palliative care and the requirements will be developed for a hardware-software complex for remote monitoring of patients' health at home.
Generating synthetic data is a relevant point in the machine learning community. As accessible data is limited, the generation of synthetic data is a significant point in protecting patients' privacy and having more possibilities to train a model for classification or other machine learning tasks. In this work, some generative adversarial networks (GAN) variants are discussed, and an overview is given of how generative adversarial networks can be used for data generation in different fields. In addition, some common problems of the GANs and possibilities to avoid them are shown. Different evaluation methods of the generated data are also described.
Background:
One of the most promising health care development areas is introducing telemedicine services and creating solutions based on blockchain technology. The study of systems combining both these domains indicates the ongoing expansion of digital technologies in this market segment.
Objective:
This paper aims to review the feasibility of blockchain technology for telemedicine.
Methods:
The authors identified relevant studies via systematic searches of databases including PubMed, Scopus, Web of Science, IEEE Xplore, and Google Scholar. The suitability of each for inclusion in this review was assessed independently. Owing to the lack of publications, available blockchain-based tokens were discovered via conventional web search engines (Google, Yahoo, and Yandex).
Results:
Of the 40 discovered projects, only 18 met the selection criteria. The 5 most prevalent features of the available solutions (N=18) were medical data access (14/18, 78%), medical service processing (14/18, 78%), diagnostic support (10/18, 56%), payment transactions (10/18, 56%), and fundraising for telemedical instrument development (5/18, 28%).
Conclusions:
These different features (eg, medical data access, medical service processing, epidemiology reporting, diagnostic support, and treatment support) allow us to discuss the possibilities for integration of blockchain technology into telemedicine and health care on different levels. In this area, a wide range of tasks can be identified that could be accomplished based on digital technologies using blockchains.
To evaluate the quality of a person's sleep it is essential to identify the sleep stages and their durations. Currently, the gold standard in terms of sleep analysis is overnight polysomnography (PSG), during which several techniques like EEG (eletroencephalogram), EOG (electrooculogram), EMG (electromyogram), ECG (electrocardiogram), SpO2 (blood oxygen saturation) and for example respiratory airflow and respiratory effort are recorded. These expensive and complex procedures, applied in sleep laboratories, are invasive and unfamiliar for the subjects and it is a reason why it might have an impact on the recorded data. These are the main reasons why low-cost home diagnostic systems are likely to be advantageous. Their aim is to reach a larger population by reducing the number of parameters recorded. Nowadays, many wearable devices promise to measure sleep quality using only the ECG and body-movement signals. This work presents an android application developed in order to proof the accuracy of an algorithm published in the sleep literature. The algorithm uses ECG and body movement recordings to estimate sleep stages. The pre-recorded signals fed into the algorithm have been taken from physionet1 online database. The obtained results have been compared with those of the standard method used in PSG. The mean agreement ratios between the sleep stages REM, Wake, NREM-1, NREM-2 and NREM-3 were 38.1%, 14%, 16%, 75% and 54.3%.
To assess the quality of a person’s sleep, it is essential to examine the sleep behaviour by identifying the several sleep stages, their durations and sleep cycles. The established and gold standard procedure for sleep stage scoring is overnight polysomnography (PSG) with the Rechtschaffen and Kales (R-K) method. Unfortunately, the conduct of PSG is timeconsuming and unfamiliar for the subjects and might have an impact of the recorded data. To avoid the disadvantages with PSG, it is important to make further investigations in low-cost home diagnostic systems. For this intention it is necessary to find suitable bio vital parameters for classifying sleep stages without any physical impairments at the same time.
Due to the promising results in several publications we want to analyse existing methods for sleep stage classification based on the parameters body movement,
heartbeat and respiration. Our aim was to find different behaviour patterns in the several sleep stages. Therefore, the average values of 15 wholenight PSG recordings -obtained from the ‘DREAMS Subjects Database’- where analysed in the light of heartbeat, body movement and respiration with 10 different methods.
The exposure to the light has a great influence on human beings in their everyday life. Various lighting sources produce light that reaches the human eye and influences a rhythmic release of melatonin hormone, that is a sleep promoting factor.
Since the development of new technologies provides more control over illuminance, this work uses an IoT based lighting system to set up dim and bright scenarios. A small study has been performed on the influence of illuminance on sleep latency. The system consists of different light bulbs, sensors and a central bridge which are interconnected like a mesh network. Also, a mobile app has been developed, that allows to adjust the lighting in various rooms. With the help of a ferro-electret sensor, like applied in sleep monitoring systems, a subject’s sleep was monitored. The sensor is placed below the mattress and it collects data, which is stored and processed in a cloud or in other alternative locations.
The research was conducted on healthy young subjects after being previously exposed to the preconfigured illuminance for at least three hours before bedtime. The results indicate correlation between sleep onset latency and exposure to different illuminance before bedtime. In a dimmed environment, the subject fell asleep in average 28% faster compared to the brighter environment.
The proposed approach applies current unsupervised clustering approaches in a different dynamic manner. Instead of taking all the data as input and finding clusters among them, the given approach clusters Holter ECG data (long-term electrocardiography data from a holter monitor) on a given interval which enables a dynamic clustering approach (DCA). Therefore advanced clustering techniques based on the well known Dynamic Time Warping algorithm are used. Having clusters e.g. on a daily basis, clusters can be compared by defining cluster shape properties. Doing this gives a measure for variation in unsupervised cluster shapes and may reveal unknown changes in healthiness. Embedding this approach into wearable devices offers advantages over the current techniques. On the one hand users get feedback if their ECG data characteristic changes unforeseeable over time which makes early detection possible. On the other hand cluster properties like biggest or smallest cluster may help a doctor in making diagnoses or observing several patients. Further, on found clusters known processing techniques like stress detection or arrhythmia classification may be applied.
Sleep is essential to existence, much like air, water, and food, as we spend nearly one-third of our time sleeping. Poor sleep quality or disturbed sleep causes daytime solemnity, which worsens daytime activities' mental and physical qualities and raises the risk of accidents. With advancements in sensor and communication technology, sleep monitoring is moving out of specialized clinics and into our everyday homes. It is possible to extract data from traditional overnight polysomnographic recordings using more basic tools and straightforward techniques. Ballistocardiogram is an unobtrusive, non-invasive, simple, and low-cost technique for measuring cardiorespiratory parameters. In this work, we present a sensor board interface to facilitate the communication between force sensitive resistor sensor and an embedded system to provide a high-performing prototype with an efficient signal-to-noise ratio. We have utilized a multi-physical-layer approach to locate each layer on top of another, yet supporting a low-cost, compact design with easy deployment under the bed frame.
Apnea is a sleep disorder characterized by breathing interruptions during sleep, impacting cardiorespiratory function and overall health. Traditional diagnostic methods, like polysomnography (PSG), are unobtrusive, leading to noninvasive monitoring. This study aims to develop and validate a novel sleep monitoring system using noninvasive sensor technology to estimate cardiorespiratory parameters and detect sleep apnea. We designed a seamless monitoring system integrating noncontact force-sensitive resistor sensors to collect ballistocardiogram signals associated with cardiorespiratory activity. We enhanced the sensor’s sensitivity and reduced the noise by designing a new concept of edge-measuring sensor using a hemisphere dome and mechanical hanger to distribute the force and mechanically amplify the micromovement caused by cardiac and respiration activities. In total, we deployed three edge-measuring sensors, two deployed under the thoracic and one under the abdominal regions. The system is supported with onboard signal preprocessing in multiple physical layers deployed under the mattress. We collected the data in four sleeping positions from 16 subjects and analyzed them using ensemble empirical mode decomposition (EMD) to avoid frequency mixing. We also developed an adaptive thresholding method to identify sleep apnea. The error was reduced to 3.98 and 1.43 beats/min (BPM) in heart rate (HR) and respiration estimation, respectively. The apnea was detected with an accuracy of 87%. We optimized the system such that only one edge-measuring sensor can measure the cardiorespiratory parameters. Such a reduction in the complexity and simplification of the instruction of use shows excellent potential for in-home and continuous monitoring.
Sleep disorders can impact daily life, affecting physical, emotional, and cognitive well-being. Due to the time-consuming, highly obtrusive, and expensive nature of using the standard approaches such as polysomnography, it is of great interest to develop a noninvasive and unobtrusive in-home sleep monitoring system that can reliably and accurately measure cardiorespiratory parameters while causing minimal discomfort to the user’s sleep. We developed a low-cost Out of Center Sleep Testing (OCST) system with low complexity to measure cardiorespiratory parameters. We tested and validated two force-sensitive resistor strip sensors under the bed mattress covering the thoracic and abdominal regions. Twenty subjects were recruited, including 12 males and 8 females. The ballistocardiogram signal was processed using the 4th smooth level of the discrete wavelet transform and the 2nd order of the Butterworth bandpass filter to measure the heart rate and respiration rate, respectively. We reached a total error (concerning the reference sensors) of 3.24 beats per minute and 2.32 rates for heart rate and respiration rate, respectively. For males and females, heart rate errors were 3.47 and 2.68, and respiration rate errors were 2.32 and 2.33, respectively. We developed and verified the reliability and applicability of the system. It showed a minor dependency on sleeping positions, one of the major cumbersome sleep measurements. We identified the sensor under the thoracic region as the optimal configuration for cardiorespiratory measurement. Although testing the system with healthy subjects and regular patterns of cardiorespiratory parameters showed promising results, further investigation is required with the bandwidth frequency and validation of the system with larger groups of subjects, including patients.
Fatigue and drowsiness are responsible for a significant percentage of road traffic accidents. There are several approaches to monitor the driver’s drowsiness, ranging from the driver’s steering behavior to analysis of the driver, e.g. eye tracking, blinking, yawning or electrocardiogram (ECG). This paper describes the development of a low-cost ECG sensor to derive heart rate variability (HRV) data for the drowsiness detection. The work includes the hardware and the software design. The hardware has been implemented on a printed circuit board (PCB) designed so that the board can be used as an extension shield for an Arduino. The PCB contains a double, inverted ECG channel including low-pass filtering and provides two analog outputs to the Arduino, that combined them and performs the analog-to-digital conversion. The digital ECG signal is transferred to an NVidia embedded PC where the processing takes place, including QRS-complex, heart rate and HRV detection as well as visualization features. The compact resulting sensor provides good results in the extraction of the main ECG parameters. The sensor is being used in a larger frame, where facial-recognition-based drowsiness detection is combined with ECG-based detection to improve the recognition rate under unfavorable light or occlusion conditions.
The person’s heart rate is an important indicator of their health status. A heart rate that is too high or too low could be a sign of several different diseases, such as a heart disorder, obesity, asthma, or many others. Many devices require users to wear the device on their chest or place a finger on the device. The approach presented in this paper describes the principle and implementation of a heart rate monitoring device, which is able to detect the heart rate with high precision with the sensor integrated in a wristband. One method to measure the heart rate is the photoplethysmogram technique. This method measures the change of blood volume through the absorption or reflection of light. A light emitting diode (LED) shines through a thin amount of tissue. A photo-diode registers the intensity of light that traverses the tissue or is reflected by the tissue. Since blood changes its volume with each heartbeat, the photo-diode detects more or less light from the LED. The device is able to measure the heart rate with a high precision, it has low performance and hardware requirements, and it allows an implementation with small micro-controllers.
Polysomnography is a gold standard for a sleep study, and it provides very accurate results, but its cost (both personnel and material) are quite high. Therefore, the development of a low-cost system for overnight breathing and heartbeat monitoring, which provides more comfort while recording the data, is a well-motivated challenge. The system proposed in this manuscript is based on the usage of resistive pressure sensors installed under the mattress. These sensors can measure slight pressure changes provoked during breathing and heartbeat. The captured signal requires advanced processing, like applying filters and amplifiers before the analog signal is ready for the next step. Then, the output signal is digitalized and further processed by an algorithm that performs a custom filtering before it can recognize breathing and heart rate in real-time. The result can be directly visualized. Furthermore, a CSV file is created containing the raw data, timestamps, and unique IDs to facilitate further processing. The achieved results are promising, and the average deviation from a reference device is about 4bpm.
Normal breathing during sleep is essential for people’s health and well-being. Therefore, it is crucial to diagnose apnoea events at an early stage and apply appropriate therapy. Detection of sleep apnoea is a central goal of the system design described in this article. To develop a correctly functioning system, it is first necessary to define the requirements outlined in this manuscript clearly. Furthermore, the selection of appropriate technology for the measurement of respiration is of great importance. Therefore, after performing initial literature research, we have analysed in detail three different methods and made a selection of a proper one according to determined requirements. After considering all the advantages and disadvantages of the three approaches, we decided to use the impedance measurement-based one. As a next step, an initial conceptual design of the algorithm for detecting apnoea events was created. As a result, we developed an activity diagram on which the main system components and data flows are visually represented.
In recent decades, it can be observed that a steady increase in the volume of tourism is a stable trend. To offer travel opportunities to all groups, it is also necessary to prepare offers for people in need of long-term care or people with disabilities. One of the ways to improve accessibility could be digital technologies, which could help in planning as well as in carrying out trips. In the work presented, a study of barriers was first conducted, which led to selecting technologies for a test setup after analysis. The main focus was on a mobile app with travel information and 360° tours. The evaluation results showed that both technologies could increase accessibility, but some essential aspects (such as usability, completeness, relevance, etc.) need to be considered when implementing them.
The process of restoring our body and brain from fatigue is directly depend-ing on the quality of sleep. It can be determined from the report of the sleep study results. Classification of sleep stages is the first step of this study and this includes the measurement of biovital data and its further processing.
In this work, the sleep analysis system is based on a hardware sensor net, namely a grid of 24 pressure sensors, supporting sleep phase recognition. In comparison to the leading standard, which is polysomnography, the proposed approach is a non-invasive system. It recognises respiration and body move-ment with only one type of low-cost pressure sensors forming a mesh archi-tecture. The nodes implement as a series of pressure sensors connected to a low-power and performant microcontroller. All nodes are connected via a system wide bus with address arbitration. The embedded processor is the mesh network endpoint that enables network configuration, storing and pre-processing of the data, external data access and visualization.
The system was tested by executing experiments recording the sleep of different healthy young subjects. The results obtained have indicated the po-tential to detect breathing rate and body movement. A major difference of this system in comparison to other approaches is the innovative way to place the sensors under the mattress. This characteristic facilitates the continuous using of the system without any influence on the common sleep process.
The scoring of sleep stages is one of the essential tasks in sleep analysis. Since a manual procedure requires considerable human and financial resources, and incorporates some subjectivity, an automated approach could result in several advantages. There have been many developments in this area, and in order to provide a comprehensive overview, it is essential to review relevant recent works and summarise the characteristics of the approaches, which is the main aim of this article. To achieve it, we examined articles published between 2018 and 2022 that dealt with the automated scoring of sleep stages. In the final selection for in-depth analysis, 125 articles were included after reviewing a total of 515 publications. The results revealed that automatic scoring demonstrates good quality (with Cohen's kappa up to over 0.80 and accuracy up to over 90%) in analysing EEG/EEG + EOG + EMG signals. At the same time, it should be noted that there has been no breakthrough in the quality of results using these signals in recent years. Systems involving other signals that could potentially be acquired more conveniently for the user (e.g. respiratory, cardiac or movement signals) remain more challenging in the implementation with a high level of reliability but have considerable innovation capability. In general, automatic sleep stage scoring has excellent potential to assist medical professionals while providing an objective assessment.
Healthy sleep is one of the prerequisites for a good human body and brain condition, including general well-being. Unfortunately, there are several sleep disorders that can negatively affect this. One of the most common is sleep apnoea, in which breathing is impaired. Studies have shown that this disorder often remains undiagnosed. To avoid this, developing a system that can be widely used in a home environment to detect apnoea and monitor the changes once therapy has been initiated is essential. The conceptualisation of such a system is the main aim of this research. After a thorough analysis of the available literature and state of the art in this area of knowledge, a concept of the system was created, which includes the following main components: data acquisition (including two parts), storage of the data, apnoea detection algorithm, user and device management, data visualisation. The modules are interchangeable, and interfaces have been defined for data transfer, most of which operate using the MQTT protocol. System diagrams and detailed component descriptions, including signal requirements and visualisation mockups, have also been developed. The system's design includes the necessary concepts for the implementation and can be realised in a prototype in the next phase.
The last decades have shown that the volume of tourism, in general, is constantly increasing (with some justified exceptions). To offer a possibility of travel for all groups of people, it is necessary to pay attention to accessibility. One of the possibilities for increasing accessibility is digital technologies, which could assist in planning and the implementation and completion of trips. To make a selection of technologies, first, a study of barriers was conducted, which was then analyzed, and finally, some technologies were made available in a test setup. A focus on two technologies was made: 360°-Tours and mobile app with the travel information. The two technologies were implemented and presented to the test subjects.
The evaluation results showed that both technologies could increase accessibility if some essential aspects (such as usability, completeness, relevance, etc.) are considered during the implementation.
This paper presents a bed system able to analyze a person’s movement, breathing and recognize the positions that the subject is lying on the bed during the night without any additional physical contact. The measurements are performed with sensors placed between the mattress and the bed-frame. An Intel Edison board was used as an endpoint that served as a communication node from the mesh network to external service. Two nodes and Intel Edison are attached to the bottom of the bed frame and they are connected to the sensors. First test results have indicated the potential of the proposed approach for the recognition of sleep positions with 83% of correct recognized positions.
This document presents an algorithm for a non-obtrusive recognition of Sleep/Wake states using signals derived from ECG, respiration, and body movement captured while lying in a bed. As a core mathematical base of system data analytics, multinomial logistic regression techniques were chosen. Derived parameters of the three signals are used as the input for the proposed method. The overall achieved accuracy rate is 84% for Wake/Sleep stages, with Cohen’s kappa value 0.46. The presented algorithm should support experts in analyzing sleep quality in more detail. The results confirm the potential of this method and disclose several ways for its improvement.
Das häusliche Umfeld kann vor allem für langfristiges Schlafmonitoring verwendet werden. Gute Patientenakzeptanz erfordert niedrige Nutzer- und Installationsbarrieren. Für die Installation zu Hause sind klassische PSG-Systeme aufgrund von ihrer Komplexität wenig passend. Ziel der Entwicklung ist die qualifizierte Erhebung von Parametern, die einerseits eine hinreichend gute Klassifikation von Schlafphasen erlauben und die andererseits durch nicht-invasive Methoden erfasst werden können.
Basierend auf einer Literaturstudie und der Maßgabe nicht-invasive Methoden zu nutzen, wurden folgende Parameter ausgewählt: Körperbewegung, Atmung und Herzschlag. Diese Parameter können nicht-invasiv durch Matratzendrucksensoren erfasst werden. Die Sensorknoten sind als ein Netz von Drucksensoren implementiert, die mit einem leistungsarmen und performanten Mikrocontroller verbunden sind. Alle Knoten sind über einen systemweiten Bus mit Adressarbitrierung verbunden. Der eingebettete Prozessor ist der Mesh-Netzwerk-Endpunkt, der die Netzwerkkonfiguration, Speicherung und Vorverarbeitung der Daten, externen Datenzugriff und Visualisierung ermöglicht.
Das System wurde getestet, indem Experimente durchgeführt wurden, die den Schlaf verschiedener gesunder junger Personen aufzeichneten. Die erhaltenen Ergebnisse bestätigen die Fähigkeit des Systems, Atemfrequenz und Körperbewegung zu erfassen. Ein wesentlicher Unterschied dieses Systems im Vergleich zu anderen Ansätzen ist die innovative Art, die Sensoren unter der Matratze zu platzieren. Diese Eigenschaft erleichtert die kontinuierliche Nutzung des Systems ohne Einfluss auf den gemeinsamen Schlafprozess.
Um Schlafverhalten langfristig zu untersuchen, wird ein Hardwaresystem mit niedrigen Installationsbarrieren für den Einsatz im häuslichen Umfeld. Erste Ergebnisse weisen auf das Potenzial hin, außer Körperbewegung und Atemfrequenz, auch Herzfrequenz erfassen zu können. Die Werte können weiter verbessert werden, wenn die Sensorabfragefrequenz erhöht wird. Nach der Weiterentwicklung des Systems, soll es mit dem Softwarealgorithmus für die Schlafphasenerkennung verbunden werden.
Die Schlafapnoe ist eine häufig auftretende Schlafstörung,
die unterschiedliche Auswirkungen auf unseren Alltag hat; so wurde z. B.
über eine Tagesschläfrigkeit von etwa 25 % der Patienten mit obstruktiver
Schlafapnoe (OSA) berichtet. Ziel dieser Arbeit ist die Entwicklung eines
Systems, das eine nichtinvasive Erkennung der Schlafapnoe in häuslicher
Umgebung ermöglichen soll.
Good sleep is crucial for a healthy life of every person. Unfortunately, its quality often decreases with aging. A common approach to measuring the sleep characteristics is based on interviews with the subjects or letting them fill in a daily questionnaire and afterward evaluating the obtained data. However, this method has time and personal costs for the interviewer and evaluator of responses. Therefore, it would be important to execute the collection and evaluation of sleep characteristics automatically. To do that, it is necessary to investigate the level of agreement between measurements performed in a traditional way using questionnaires and measurements obtained using electronic monitoring devices. The study presented in this manuscript performs this investigation, comparing such sleep characteristics as "time going to bed", "total time in bed", "total sleep time" and "sleep efficiency". A total number of 106 night records of elderly persons (aged 65+) were analyzed. The results achieved so far reveal the fact that the degree of agreement between the two measurement methods varies substantially for different characteristics, from 31 minutes of mean difference for "time going to bed" to 77 minutes for "total sleep time". For this reason, a direct exchange of objective and subjective measuring methods is currently not possible.
Sleep study can be used for detection of sleep quality and in general bed behaviors. These results can helpful for regulating sleep and recognizing different sleeping disorders of human. In comparison to the leading standard measuring system, which is Polysomnography (PSG), the system proposed in this work is a non-invasive sleep monitoring device. For continuous analysis or home use, the PSG or wearable Actigraphy devices tends to be uncomfortable. Besides, these methods not only decrease practicality due to the process of having to put them on, but they are also very expensive. The system proposed in this paper classifies respiration and body movement with only one type of sensor and also in a noninvasive way. The sensor used is a pressure sensor. This sensor is low cost and can be used for commercial proposes. The system was tested by carrying out an experiment that recorded the sleep process of a subject. These recordings showed excellent results in the classification of breathing rate and body movements.
Recognition of sleep and wake states is one of the relevant parts of sleep analysis. Performing this measurement in a contactless way increases comfort for the users. We present an approach evaluating only movement and respiratory signals to achieve recognition, which can be measured non-obtrusively. The algorithm is based on multinomial logistic regression and analyses features extracted out of mentioned above signals. These features were identified and developed after performing fundamental research on characteristics of vital signals during sleep. The achieved accuracy of 87% with the Cohen’s kappa of 0.40 demonstrates the appropriateness of a chosen method and encourages continuing research on this topic.
Das klinische Standardverfahren und Referenz der Schlafmessung und der Klassifizierung der einzelnen Schlafstadien ist die Polysomnographie (PSG). Alternative Ansätze zu diesem aufwändigen Verfahren könnten einige Vorteile bieten, wenn die Messungen auf eine komfortablere Weise durchgeführt werden. Das Hauptziel dieser Forschung Studie ist es, einen Algorithmus für die automatische Klassifizierung von Schlafstadien zu entwickeln, der ausschließlich Bewegungs- und Atmungssignale verwendet.