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This thesis emphasizes problems that reports generated by vulnerability scanners impose on the process of vulnerability management, which are a. an overwhelming amount of data and b. an insufficient prioritization of the scan results.
To assist the process of developing means to counteract those problems and to allow for quantitative evaluation of their solutions, two metrics are proposed for their effectiveness and efficiency. These metrics imply a focus on higher severity vulnerabilities and can be applied to any simplification process of vulnerability scan results, given it relies on a severity score and time of remediation estimation for each vulnerability.
A priority score is introduced which aims to improve the widely used Common Vulnerability Scoring System (CVSS) base score of each vulnerability dependent on a vulnerability’s ease of exploit, estimated probability of exploitation and probability of its existence.
Patterns within the reports generated by the Open Vulnerability Assessment System (OpenVAS) vulnerability scanner between vulnerabilities are discovered which identify criteria by which they can be categorized from a remediation actor standpoint. These categories lay the groundwork of a final simplified report and consist of updates that need to be installed on a host, severe vulnerabilities, vulnerabilities that occur on multiple hosts and vulnerabilities that will take a lot of time for remediation. The highest potential time savings are found to exist within frequently occurring vulnerabilities, minor- and major suggested updates.
Processing of the results provided by the vulnerability scanner and creation of the report is realized in the form of a python script. The resulting reports are short, straight to the point and provide a top down remediation process which should theoretically allow to minimize the institutions attack surface as fast as possible. Evaluation of the practicality must follow as the reports are yet to be introduced into the Information Security Management Lifecycle.
The influence of sleep on human life, including physiological, psychological, and mental aspects, is remarkable. Therefore, it is essential to apply appropriate therapy in the case of sleep disorders. For this, however, the irregularities must first be recognised, preferably conveniently for the person concerned. This dissertation, structured as a composition of research articles, presents the development of mathematically based algorithmic principles for a sleep analysis system. The particular focus is on the classification of sleep stages with a minimal set of physiological parameters. In addition, the aspects of using the sleep analysis system as part of the more complex healthcare systems are explored. Design of hardware for non-obtrusive measurement of relevant physiological parameters and the use of such systems to detect other sleep disorders, such as sleep apnoea, are also referred to. Multinomial logistic regression was selected as the basis for development resulting from the investigations carried out. By following a methodical procedure, the number of physiological parameters necessary for the classification of sleep stages was successively reduced to two: Respiratory and Movement signals. These signals might be measured in a contactless way. A prototype implementation of the developed algorithms was performed to validate the proposed method, and the evaluation of 19324 sleep epochs was carried out. The results, with the achieved accuracy of 73% in the classification of Wake/NREM/REM stages and Cohen's kappa of 0.44, outperform the state of the art and demonstrate the appropriateness of the selected approach. In the future, this method could enable convenient, cost-effective, and accurate sleep analysis, leading to the detection of sleep disorders at an early stage so that therapy can be initiated as soon as possible, thus improving the general population's health status and quality of life.
Die digitale Transformation von Geschäftsprozessen und die stärkere Einbindung von IT-Systemen erzeugen bei kleinen und mittelständischen Unternehmen (KMU) Chancen und Risiken zugleich. Risiken, die insbesondere in einer fehlenden IT-Compliance resultieren können. Wie Studien zeigen, sind KMU in Bezug auf IT-Compliance-Maßnahmen im Vergleich zu kapitalmarktorientierten Unternehmen jedoch im Rückstand [1]. Im Beitrag wird mithilfe von Experteninterviews und einer qualitativen Datenanalyse der Frage nachgegangen, welcher Status quo an Maßnahmen aktuell implementiert und wie der empfundene Compliance-Reifegrad ist. Weiterhin werden die Gründe und Motive erörtert, die zu diesem Zustand geführt haben. Letztlich sind Treiber identifiziert worden, die zu einem höheren Bewusstsein in der Zukunft führen können. Die Arbeit zeigt interessante Erkenntnisse aus der Praxis, da die Experteninterviews Einblicke in den aktuellen Status quo in Bezug auf IT-Compliance liefern.
Der Gegenstand dieser Bachelorarbeit ist die automatisierte Extraktion von Polygonzügen anhand eines Grundrissbildes. Diese Polygonzüge sollen die Räumlichkeiten wiedergeben. In dieser Bachelorarbeit wurde daher ein Algorithmus für die Grundrissbildverarbeitung mittels Python entwickelt und implementiert. Zuerst wird ein Grundrissbild bereinigt, d. h. es werden unerwünschte Bildstrukturen verwaschen. Mithilfe des Canny-Kantendetektors werden anschließend die Kanten detektiert. Danach werden die Ecken im Grundrissbild via Harris-Eckendetektor lokalisiert. Um die Ecken sinnvoll zu verbinden, wird eine abgewandelte Form des Dijkstra Algorithmus herangezogen. Die daraus gewonnen Daten dienen zur Erstellung der Polygonzüge, welche für die Simulation von pFlow benötigt werden. Der entwickelte Algorithmus eignet sich insbesondere für klare und simple Grundrissbilder.
Interpretability and uncertainty modeling are important key factors for medical applications. Moreover, data in medicine are often available as a combination of unstructured data like images and structured predictors like patient’s metadata. While deep learning models are state-of-the-art for image classification, the models are often referred to as ’black-box’, caused by the lack of interpretability. Moreover, DL models are often yielding point predictions and are too confident about the parameter estimation and outcome predictions.
On the other side with statistical regression models, it is possible to obtain interpretable predictor effects and capture parameter and model uncertainty based on the Bayesian approach. In this thesis, a publicly available melanoma dataset, consisting of skin lesions and patient’s age, is used to predict the melanoma types by using a semi-structured model, while interpretable components and model uncertainty is quantified. For Bayesian models, transformation model-based variational inference (TM-VI) method is used to determine the posterior distribution of the parameter. Several model constellations consisting of patient’s age and/or skin lesion were implemented and evaluated. Predictive performance was shown to be best by using a combined model of image and patient’s age, while providing the interpretable posterior distribution of the regression coefficient is possible. In addition, integrating uncertainty in image and tabular parts results in larger variability of the outputs corresponding to high uncertainty of the single model components.
Background:
One of the most promising health care development areas is introducing telemedicine services and creating solutions based on blockchain technology. The study of systems combining both these domains indicates the ongoing expansion of digital technologies in this market segment.
Objective:
This paper aims to review the feasibility of blockchain technology for telemedicine.
Methods:
The authors identified relevant studies via systematic searches of databases including PubMed, Scopus, Web of Science, IEEE Xplore, and Google Scholar. The suitability of each for inclusion in this review was assessed independently. Owing to the lack of publications, available blockchain-based tokens were discovered via conventional web search engines (Google, Yahoo, and Yandex).
Results:
Of the 40 discovered projects, only 18 met the selection criteria. The 5 most prevalent features of the available solutions (N=18) were medical data access (14/18, 78%), medical service processing (14/18, 78%), diagnostic support (10/18, 56%), payment transactions (10/18, 56%), and fundraising for telemedical instrument development (5/18, 28%).
Conclusions:
These different features (eg, medical data access, medical service processing, epidemiology reporting, diagnostic support, and treatment support) allow us to discuss the possibilities for integration of blockchain technology into telemedicine and health care on different levels. In this area, a wide range of tasks can be identified that could be accomplished based on digital technologies using blockchains.
Preliminary results of homomorphic deconvolution application to surface EMG signals during walking
(2021)
Homomorphic deconvolution is applied to sEMG signals recorded during walking. Gastrocnemius lateralis and tibialis anterior signals were acquired according to SENIAM recommendation. MUAP parameters like amplitude and scale were estimated, whilst the MUAP shape parameter was fixed. This features a useful time-frequency representation of sEMG signal. Estimation of scale MUAP parameter was verified extracting the mean frequency of filtered EMG signal, extracted from the scale parameter estimated with two different MUAP shape values.
Normal breathing during sleep is essential for people’s health and well-being. Therefore, it is crucial to diagnose apnoea events at an early stage and apply appropriate therapy. Detection of sleep apnoea is a central goal of the system design described in this article. To develop a correctly functioning system, it is first necessary to define the requirements outlined in this manuscript clearly. Furthermore, the selection of appropriate technology for the measurement of respiration is of great importance. Therefore, after performing initial literature research, we have analysed in detail three different methods and made a selection of a proper one according to determined requirements. After considering all the advantages and disadvantages of the three approaches, we decided to use the impedance measurement-based one. As a next step, an initial conceptual design of the algorithm for detecting apnoea events was created. As a result, we developed an activity diagram on which the main system components and data flows are visually represented.
Respiratory diseases are leading causes of death and disability in the world. The recent COVID-19 pandemic is also affecting the respiratory system. Detecting and diagnosing respiratory diseases requires both medical professionals and the clinical environment. Most of the techniques used up to date were also invasive or expensive.
Some research groups are developing hardware devices and techniques to make possible a non-invasive or even remote respiratory sound acquisition. These sounds are then processed and analysed for clinical, scientific, or educational purposes.
We present the literature review of non-invasive sound acquisition devices and techniques.
The results are about a huge number of digital tools, like microphones, wearables, or Internet of Thing devices, that can be used in this scope.
Some interesting applications have been found. Some devices make easier the sound acquisition in a clinic environment, but others make possible daily monitoring outside that ambient. We aim to use some of these devices and include the non-invasive recorded respiratory sounds in a Digital Twin system for personalized health.
A residual neural network was adapted and applied to the Physionet/Computing data in Cardiology Challenge 2020 to detect 24 different classes of cardiac abnormalities from 12-lead. Additive Gaussian noise, signal shifting, and the classification of signal sections of different lengths were applied to prevent the network from overfitting and facilitating generalization. Due to the use of a global pooling layer after the feature extractor, the network is independent of the signal’s length. On the hidden test set of the challenge, the model achieved a validation score of 0.656 and a full test score of 0.27, placing us 15th out of 41 officially ranked teams (Team name: UC_Lab_Kn). These results show the potential of deep neural networks for ap- plication to raw data and a complex multi-class multi-label classification problem, even if the training data is from di- verse datasets and of differing lengths.
We compared vulnerable and fixed versions of the source code of 50 different PHP open source projects based on CVE reports for SQL injection vulnerabilities. We scanned the source code with commercial and open source tools for static code analysis. Our results show that five current state-of-the-art tools have issues correctly marking vulnerable and safe code. We identify 25 code patterns that are not detected as a vulnerability by at least one of the tools and 6 code patterns that are mistakenly reported as a vulnerability that cannot be confirmed by manual code inspection. Knowledge of the patterns could help vendors of static code analysis tools, and software developers could be instructed to avoid patterns that confuse automated tools.
The evaluation of the effectiveness of different machine learning algorithms on a publicly available database of signals derived from wearable devices is presented with the goal of optimizing human activity recognition and classification. Among the wide number of body signals we choose a couple of signals, namely photoplethysmographic (optically detected subcutaneous blood volume) and tri-axis acceleration signals that are easy to be simultaneously acquired using commercial widespread devices (e.g. smartwatches) as well as custom wearable wireless devices designed for sport, healthcare, or clinical purposes. To this end, two widely used algorithms (decision tree and k-nearest neighbor) were tested, and their performance were compared to two new recent algorithms (particle Bernstein and a Monte Carlo-based regression) both in terms of accuracy and processing time. A data preprocessing phase was also considered to improve the performance of the machine learning procedures, in order to reduce the problem size and a detailed analysis of the compression strategy and results is also presented.
Good sleep is crucial for a healthy life of every person. Unfortunately, its quality often decreases with aging. A common approach to measuring the sleep characteristics is based on interviews with the subjects or letting them fill in a daily questionnaire and afterward evaluating the obtained data. However, this method has time and personal costs for the interviewer and evaluator of responses. Therefore, it would be important to execute the collection and evaluation of sleep characteristics automatically. To do that, it is necessary to investigate the level of agreement between measurements performed in a traditional way using questionnaires and measurements obtained using electronic monitoring devices. The study presented in this manuscript performs this investigation, comparing such sleep characteristics as "time going to bed", "total time in bed", "total sleep time" and "sleep efficiency". A total number of 106 night records of elderly persons (aged 65+) were analyzed. The results achieved so far reveal the fact that the degree of agreement between the two measurement methods varies substantially for different characteristics, from 31 minutes of mean difference for "time going to bed" to 77 minutes for "total sleep time". For this reason, a direct exchange of objective and subjective measuring methods is currently not possible.
Polysomnography is a gold standard for a sleep study, and it provides very accurate results, but its cost (both personnel and material) are quite high. Therefore, the development of a low-cost system for overnight breathing and heartbeat monitoring, which provides more comfort while recording the data, is a well-motivated challenge. The system proposed in this manuscript is based on the usage of resistive pressure sensors installed under the mattress. These sensors can measure slight pressure changes provoked during breathing and heartbeat. The captured signal requires advanced processing, like applying filters and amplifiers before the analog signal is ready for the next step. Then, the output signal is digitalized and further processed by an algorithm that performs a custom filtering before it can recognize breathing and heart rate in real-time. The result can be directly visualized. Furthermore, a CSV file is created containing the raw data, timestamps, and unique IDs to facilitate further processing. The achieved results are promising, and the average deviation from a reference device is about 4bpm.
Cardiovascular diseases are directly or indirectly responsible for up to 38.5% of all deaths in Germany and thus represent the most frequent cause of death. At present, heart diseases are mainly discovered by chance during routine visits to the doctor or when acute symptoms occur. However, there is no practical method to proactively detect diseases or abnormalities of the heart in the daily environment and to take preventive measures for the person concerned. Long-term ECG devices, as currently used by physicians, are simply too expensive, impractical, and not widely available for everyday use. This work aims to develop an ECG device suitable for everyday use that can be worn directly on the body. For this purpose, an already existing hardware platform will be analyzed, and the corresponding potential for improvement will be identified. A precise picture of the existing data quality is obtained by metrological examination, and corresponding requirements are defined. Based on these identified optimization potentials, a new ECG device is developed. The revised ECG device is characterized by a high integration density and combines all components directly on one board except the battery and the ECG electrodes. The compact design allows the device to be attached directly to the chest. An integrated microcontroller allows digital signal processing without the need for an additional computer. Central features of the evaluation are a peak detection for detecting R-peaks and a calculation of the current heart rate based on the RR interval. To ensure the validity of the detected R-peaks, a model of the anatomical conditions is used. Thus, unrealistic RR-intervals can be excluded. The wireless interface allows continuous transmission of the calculated heart rate. Following the development of hardware and software, the results are verified, and appropriate conclusions about the data quality are drawn. As a result, a very compact and wearable ECG device with different wireless technologies, data storage, and evaluation of RR intervals was developed. Some tests yelled runtimes up to 24 hours with wireless Lan activated and streaming.
In previous studies, we used a method for detecting stress that was based exclusively on heart rate and ECG for differentiation between such situations as mental stress, physical activity, relaxation, and rest. As a response of the heart to these situations, we observed different behavior in the Root Mean Square of the Successive differences heartbeats (RMSSD). This study aims to analyze Virtual Reality via a virtual reality headset as an effective stressor for future works. The value of the Root Mean Square of the Successive Differences is an important marker for the parasympathetic effector on the heart and can provide information about stress. For these measurements, the RR interval was collected using a breast belt. In these studies, we can observe the Root Mean Square of the successive differences heartbeats. Additional sensors for the analysis were not used. We conducted experiments with ten subjects that had to drive a simulator for 25 minutes using monitors and 25 minutes using virtual reality headset. Before starting and after finishing each simulation, the subjects had to complete a survey in which they had to describe their mental state. The experiment results show that driving using virtual reality headset has some influence on the heart rate and RMSSD, but it does not significantly increase the stress of driving.
This work is a study about a comparison of survey tools and it should help developers in selecting a suited tool for application in an AAL environment. The first step was to identify the basic required functionality of the survey tools used for AAL technologies and to compare these tools by their functionality and assignments. The comparative study was derived from the data obtained, previous literature studies and further technical data. A list of requirements was stated and ordered in terms of relevance to the target application domain. With the help of an integrated assessment method, the calculation of a generalized estimate value was performed and the result is explained. Finally, the planned application of this tool in a running project is explained.
This paper presents the implementation of deep learning methods for sleep stage detection by using three signals that can be measured in a non-invasive way: heartbeat signal, respiratory signal, and movement signal. Since signals are measurements taken during the time, the problem is seen as time-series data classification. Deep learning methods are chosen to solve the problem are convolutional neural network and long-short term memory network. Input data is structured as a time-series sequence of mentioned signals that represent 30 seconds epoch, which is a standard interval for sleep analysis. The records used belong to the overall 23 subjects, which are divided into two subsets. Records from 18 subjects were used for training the data and from 5 subjects for testing the data. For detecting four sleep stages: REM (Rapid Eye Movement), Wake, Light sleep (Stage 1 and Stage 2), and Deep sleep (Stage 3 and Stage 4), the accuracy of the model is 55%, and F1 score is 44%. For five stages: REM, Stage 1, Stage 2, Deep sleep (Stage 3 and 4), and Wake, the model gives an accuracy of 40% and F1 score of 37%.
Globalization has increased the number of road trips and vehicles. The result has been an intensification of traffic accidents, which are becoming one of the most important causes of death worldwide. Traffic accidents are often due to human error, the probability of which increases when the cognitive ability of the driver decreases. Cognitive capacity is closely related to the driver’s mental state, as well as other external factors such as the CO2 concentration inside the vehicle. The objective of this work is to analyze how these elements affect driving. We have conducted an experiment with 50 drivers who have driven for 25 min using a driving simulator. These drivers completed a survey at the start and end of the experiment to obtain information about their mental state. In addition, during the test, their stress level was monitored using biometric sensors and the state of the environment (temperature, humidity and CO2 level) was recorded. The results of the experiment show that the initial level of stress and tiredness of the driver can have a strong impact on stress, driving behavior and fatigue produced by the driving test. Other elements such as sadness and the conditions of the interior of the vehicle also cause impaired driving and affect compliance with traffic regulations.
Fatigue and drowsiness are responsible for a significant percentage of road traffic accidents. There are several approaches to monitor the driver’s drowsiness, ranging from the driver’s steering behavior to analysis of the driver, e.g. eye tracking, blinking, yawning or electrocardiogram (ECG). This paper describes the development of a low-cost ECG sensor to derive heart rate variability (HRV) data for the drowsiness detection. The work includes the hardware and the software design. The hardware has been implemented on a printed circuit board (PCB) designed so that the board can be used as an extension shield for an Arduino. The PCB contains a double, inverted ECG channel including low-pass filtering and provides two analog outputs to the Arduino, that combined them and performs the analog-to-digital conversion. The digital ECG signal is transferred to an NVidia embedded PC where the processing takes place, including QRS-complex, heart rate and HRV detection as well as visualization features. The compact resulting sensor provides good results in the extraction of the main ECG parameters. The sensor is being used in a larger frame, where facial-recognition-based drowsiness detection is combined with ECG-based detection to improve the recognition rate under unfavorable light or occlusion conditions.